{"id":"W4213235571","doi":"10.1371/journal.pgen.1010041","title":"Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination","year":2022,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; State Key Laboratory of Genetic Engineering; Universidad Complutense de Madrid; Fudan University; Institute of Genetics; National Outstanding Youth Science Fund Project of National Natural Science Foundation of China; National Natural Science Foundation of China; Chinese Academy of Sciences; University of North Carolina at Chapel Hill; National Science Foundation","keywords":"Synapsis; Biology; Demethylase; Genetics; Histone; Meiosis; Meiocyte; Histone methylation; Histone methyltransferase; Epigenetics; Mutant; DNA methylation; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002917492,0.0001332612,0.0001702039,0.00003353507,0.0004133818,0.00002486092,0.0002671323,0.00009305386,0.0004449096],"category_scores_gemma":[0.0001533476,0.00006527362,0.00004014717,0.0002654144,0.00008423975,0.00002558729,0.0003821185,0.0002175578,0.00001926511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006072959,"about_ca_system_score_gemma":0.00001520383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001464041,"about_ca_topic_score_gemma":0.00003202299,"domain_scores_codex":[0.9983603,0.0004223534,0.0001849251,0.0003667878,0.000363299,0.0003023344],"domain_scores_gemma":[0.9993841,0.0002724573,0.00008018685,0.00008164947,0.00005632193,0.0001252551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003184571,0.0001307981,0.003299771,0.000006162298,0.00002146366,0.00002943748,0.00003957354,0.00001230531,0.9937004,0.000004826724,0.000383442,0.002340009],"study_design_scores_gemma":[0.0002997649,0.0007287027,0.01625518,0.000008395099,0.0000306398,0.00005650531,0.00007472195,0.001620667,0.9759328,0.0002449825,0.004488844,0.0002587425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958489,0.002731993,0.00000200464,0.0007757025,0.00008822566,0.0002513587,0.0001794589,0.00005286941,0.00006951305],"genre_scores_gemma":[0.9982395,0.0004994539,0.0002825852,0.0001670723,0.00005610588,0.00006030363,0.0005418265,0.000002360066,0.0001508055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01776751,"threshold_uncertainty_score":0.4871448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02456858154390434,"score_gpt":0.2378885443204422,"score_spread":0.2133199627765378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}