{"id":"W4213307792","doi":"10.1200/jco.2022.40.6_suppl.tps582","title":"TROPiCS-04: Study of sacituzumab govitecan (SG) in patients (pts) with locally advanced (LA) unresectable or metastatic urothelial cancer (mUC) that has progressed after prior platinum (PLT) and checkpoint inhibitor (CPI) therapy.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Gilead Sciences","keywords":"Medicine; Internal medicine; Cancer; Chemotherapy; Phases of clinical research; Oncology; Gastroenterology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001191713,0.001401293,0.001396914,0.0004974413,0.0002382767,0.001084579,0.0008714371,0.001175774,0.00377858],"category_scores_gemma":[0.0007242641,0.0004995519,0.001376186,0.000585167,0.000814419,0.0009116112,0.0004222124,0.002486133,0.00117228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001269533,"about_ca_system_score_gemma":0.001653306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001493578,"about_ca_topic_score_gemma":0.004446786,"domain_scores_codex":[0.9996803,0.0001732991,0.00001402854,0.00004874334,0.00002953274,0.00005401887],"domain_scores_gemma":[0.9994214,0.00006660082,0.00009961478,0.00003776093,0.00003278225,0.0003418798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6750206,0.04742059,0.03381595,0.001606329,0.003228347,0.0009155923,0.000754603,0.006864632,0.05503903,0.0007869143,0.007020703,0.1675268],"study_design_scores_gemma":[0.492197,0.4629128,0.02883433,0.00008906952,0.0011305,0.001125059,0.0001848875,0.002174828,0.003550309,0.0003257291,0.007423848,0.00005166184],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908812,0.003043558,0.0003007665,0.0005262906,0.00008394851,0.001284769,0.001291651,0.0001019526,0.00248589],"genre_scores_gemma":[0.9892429,0.002832202,0.0008596854,0.0008407608,0.0001403613,0.0009745623,0.002571882,0.00003181531,0.002505836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00377858,"threshold_uncertainty_score":0.0126406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0877426200166195,"score_gpt":0.4071169907731531,"score_spread":0.3193743707565336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}