{"id":"W4213325660","doi":"10.3390/s22041592","title":"Determination of Drugs in Clinical Trials: Current Status and Outlook","year":2022,"lang":"en","type":"review","venue":"Sensors","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Clinical trial; Medicine; Drug; Intensive care medicine; Pharmacology; Medical physics; Biochemical engineering; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005532819,0.0009363528,0.002144113,0.002073677,0.0003432774,0.002108582,0.001469761,0.002103152,0.007028441],"category_scores_gemma":[0.004880426,0.0004824886,0.001128843,0.002291019,0.00115378,0.002573811,0.0008878828,0.002539045,0.002966894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000967115,"about_ca_system_score_gemma":0.002799794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007700048,"about_ca_topic_score_gemma":0.001611438,"domain_scores_codex":[0.998508,0.0004304842,0.0002088561,0.0001949015,0.0005612674,0.00009639156],"domain_scores_gemma":[0.9943641,0.003566994,0.00062013,0.00009291431,0.001097657,0.0002580677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001821034,0.0001118332,0.000309332,0.0150945,0.000101485,0.00009817728,0.00006862775,0.0002946508,0.001069915,0.004589756,0.01547561,0.9626039],"study_design_scores_gemma":[0.0001154222,0.0005840291,0.001337556,0.01070505,0.0003552963,0.00102436,0.0001259091,0.0003077817,0.001212065,0.004728997,0.9794608,0.00004270878],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002031319,0.9965172,0.0004347175,0.0008486638,0.0001820079,0.0000239432,0.00003500934,0.00001605319,0.00173925],"genre_scores_gemma":[0.001509972,0.9962505,0.0006546795,0.0006317219,0.0002348468,0.00003873209,0.00006188042,0.000004936725,0.0006127362],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007028441,"threshold_uncertainty_score":0.02926069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4575945076163762,"score_gpt":0.6019412473149922,"score_spread":0.144346739698616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}