{"id":"W4213332249","doi":"10.1093/jcag/gwab049.027","title":"A28 RESPONSE RATE OF VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE (VEOIBD) PATIENTS TO ANTI-TNF TREATMENT IS HIGHER THAN PREVIOUSLY REPORTED, BUT HIGHER DOSING IS REQUIRED-A LARGE TERTIARY SINGLE CENTER EXPERIENCE","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Medicine; Infliximab; Dosing; Inflammatory bowel disease; Internal medicine; Disease; Single Center; Crohn's disease; Retrospective cohort study; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001109499,0.0001351355,0.0004940195,0.0005713652,0.0005987481,0.0009765346,0.0003374223,0.0003167961,0.002808112],"category_scores_gemma":[0.003580488,0.0001389658,0.0003160266,0.001089503,0.0003120515,0.0002736533,0.0004424848,0.0004299917,0.0004724591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008548741,"about_ca_system_score_gemma":0.0008784349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009214131,"about_ca_topic_score_gemma":0.01385638,"domain_scores_codex":[0.998165,0.0004832754,0.0002766842,0.0002659438,0.0004937079,0.0003155427],"domain_scores_gemma":[0.9944249,0.00125274,0.002658042,0.0003144774,0.0005841989,0.0007655978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009573164,0.00005378658,0.9929163,0.00004179482,0.00002374326,0.0002955363,0.0001288399,0.00003429483,0.0003661178,0.00001896089,0.0002661132,0.005758727],"study_design_scores_gemma":[0.000009645541,0.0001394068,0.9969703,0.00003089064,0.00001361636,0.001544934,0.000293567,0.00007508184,0.000176769,0.00001086022,0.0007310379,0.000003877987],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970821,0.0009113792,0.0002141635,0.0001150004,0.00001091364,0.00001990982,0.0002957097,0.000009470258,0.001341318],"genre_scores_gemma":[0.9991137,0.000241808,0.00007884081,0.00008818079,0.0000111508,0.000008848713,0.0002317026,0.00000304261,0.0002227047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009214131,"threshold_uncertainty_score":0.01832098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007968907091076668,"score_gpt":0.2220307965487869,"score_spread":0.2140618894577103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}