{"id":"W4213332982","doi":"10.1200/jco.2022.40.6_suppl.tps191","title":"PROMISE Registry: A prostate cancer registry of outcomes and germline mutations for improved survival and treatment effectiveness.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; CHEK2; PALB2; MSH2; Prostate cancer; MSH6; Genetic testing; PTEN; Oncology; Germline; MLH1; Internal medicine; Cancer; Germline mutation; Genetics; DNA mismatch repair; Mutation; Gene; Colorectal cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005771999,0.0005481774,0.0009894482,0.003633206,0.0006414405,0.001755571,0.002054203,0.0006681252,0.0284182],"category_scores_gemma":[0.01781044,0.0004592455,0.0007026946,0.007874326,0.0002533676,0.002709736,0.003235428,0.001232889,0.01151929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001609676,"about_ca_system_score_gemma":0.006153441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00974893,"about_ca_topic_score_gemma":0.0120766,"domain_scores_codex":[0.997146,0.0007369111,0.0005247656,0.0004647474,0.0009006443,0.0002269438],"domain_scores_gemma":[0.9737403,0.004224759,0.008982016,0.00290306,0.006296725,0.003853173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001602182,0.0002268818,0.1366242,0.000874038,0.000229919,0.0001083154,0.0001379621,0.0007566008,0.0002366426,0.003179234,0.7524071,0.1036171],"study_design_scores_gemma":[0.001949697,0.001024408,0.5008654,0.001284335,0.0005813346,0.0009581232,0.000541056,0.004083572,0.001037291,0.003852196,0.4836323,0.0001903446],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.02589834,0.002003209,0.003128023,0.005810382,0.0002268669,0.001438917,0.9139821,0.00310204,0.04441013],"genre_scores_gemma":[0.1234461,0.002255924,0.009761451,0.002573257,0.0004354169,0.003663532,0.8448844,0.0009303672,0.01204948],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0284182,"threshold_uncertainty_score":0.0950684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1326945739031199,"score_gpt":0.507687326157604,"score_spread":0.3749927522544841,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}