{"id":"W4213365409","doi":"10.1002/ajh.26508","title":"Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open‐label study","year":2022,"lang":"en","type":"article","venue":"American Journal of Hematology","topic":"Blood groups and transfusion","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Autoimmune hemolytic anemia; Adverse effect; Anemia; Internal medicine; Clinical endpoint; Gastroenterology; Haptoglobin; Syk; Clinical trial; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001256399,0.001320747,0.00230266,0.0002493918,0.0003097136,0.00107294,0.0006829337,0.001328038,0.004440299],"category_scores_gemma":[0.0009876216,0.000357942,0.001318884,0.000345123,0.0005061284,0.001205579,0.0002273273,0.001907356,0.0009444404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006980285,"about_ca_system_score_gemma":0.00110793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004014173,"about_ca_topic_score_gemma":0.001465394,"domain_scores_codex":[0.9995838,0.0001503007,0.00003254936,0.0000793179,0.00007062145,0.00008343856],"domain_scores_gemma":[0.9995806,0.00006902924,0.00009956824,0.00003283534,0.00006331001,0.0001546952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5624681,0.04638413,0.008256591,0.00733845,0.007287817,0.001268379,0.0004991252,0.005851152,0.05301236,0.001267108,0.03917424,0.2671926],"study_design_scores_gemma":[0.7555951,0.2051186,0.0112549,0.0001697236,0.001017228,0.001702799,0.0001070314,0.003125518,0.004346903,0.000681202,0.01680551,0.00007542235],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673436,0.01550489,0.001635863,0.001802705,0.0004966005,0.00383243,0.004270442,0.000326865,0.004786663],"genre_scores_gemma":[0.9763438,0.007574445,0.002035841,0.002553615,0.0003461267,0.003106611,0.004340192,0.00005165115,0.003647738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004440299,"threshold_uncertainty_score":0.01485431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03779419354714667,"score_gpt":0.3875418852873847,"score_spread":0.349747691740238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}