{"id":"W4213365409","doi":"10.1002/ajh.26508","title":"Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open‐label study","year":2022,"lang":"en","type":"article","venue":"American Journal of Hematology","topic":"Blood groups and transfusion","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Autoimmune hemolytic anemia; Adverse effect; Anemia; Internal medicine; Clinical endpoint; Gastroenterology; Haptoglobin; Syk; Clinical trial; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003829628,0.0001514266,0.0009905071,0.0001176644,0.0002046446,0.00000860731,0.000300998,0.00001830654,0.00009820379],"category_scores_gemma":[0.0000340764,0.00009186651,0.0001619146,0.0002338684,0.0001834624,0.00004360245,0.00006404024,0.0001937787,8.174009e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006187513,"about_ca_system_score_gemma":0.0001495434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002023811,"about_ca_topic_score_gemma":0.000006622111,"domain_scores_codex":[0.9985061,0.0001535054,0.0007275601,0.0001565614,0.0002346966,0.000221519],"domain_scores_gemma":[0.998292,0.0004652032,0.0007168506,0.0003041518,0.0001433389,0.00007844783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04385775,0.2522884,0.07020084,0.0003423733,0.006147634,0.003706611,0.0327201,0.00006518298,0.05799196,0.0007864496,0.001185408,0.5307072],"study_design_scores_gemma":[0.3374166,0.4728967,0.01107158,0.0002275497,0.00754226,0.02435426,0.1018105,0.003490861,0.01656655,0.0001653996,0.02390333,0.0005543809],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924096,0.001983496,0.0007783066,0.003050383,0.0002751424,0.001443948,0.00002207467,0.000006417236,0.00003065829],"genre_scores_gemma":[0.9977637,0.0002647944,0.001507551,0.0002844183,0.0000345196,0.00006651312,0.000008891972,0.0000227375,0.00004690849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5301529,"threshold_uncertainty_score":0.3746207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03779419354714667,"score_gpt":0.3875418852873847,"score_spread":0.349747691740238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}