{"id":"W4213371758","doi":"10.3390/cells11040723","title":"Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; McGill University; McGill University Health Centre","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institute on Drug Abuse","keywords":"Cannabidiol; Viral load; Biology; Extracellular vesicle; Inflammation; Virology; Virus; Microvesicles; Immunology; Cannabis; Medicine; microRNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103749,0.0002405564,0.0002740068,0.0002110893,0.0001615583,0.0002467303,0.0001679151,0.0001744179,0.001488794],"category_scores_gemma":[0.0001302558,0.00006837343,0.0001843151,0.0001107912,0.0001357722,0.0001135948,0.0002030069,0.0003349814,0.0003090751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002405986,"about_ca_system_score_gemma":0.0002611306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094593,"about_ca_topic_score_gemma":0.002286135,"domain_scores_codex":[0.999885,0.00002144965,0.000009461623,0.00001394136,0.00003187532,0.00003833555],"domain_scores_gemma":[0.9999638,0.000006847046,0.00000720592,0.000005048132,0.000007175163,0.00001007472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004732606,0.00009078382,0.0002380207,0.0000855928,0.000009066808,0.00003010375,0.00002125455,0.00007501192,0.9898064,0.000119839,0.0001654026,0.008885284],"study_design_scores_gemma":[0.00004401581,0.0006680935,0.004160319,0.0000201193,0.00002080487,0.00009756706,0.00003699592,0.0006989894,0.9902474,0.00007791426,0.00392304,0.000004778429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860495,0.007847197,0.00200241,0.0001807748,0.00007263643,0.00005686757,0.0003957794,0.00009077399,0.003304142],"genre_scores_gemma":[0.9879417,0.003225724,0.002397863,0.0001099655,0.00002224437,0.00005496814,0.0003812003,0.0000169827,0.005849348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001488794,"threshold_uncertainty_score":0.004980564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009289456953947724,"score_gpt":0.2135008365726668,"score_spread":0.2042113796187191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}