{"id":"W4213376648","doi":"10.22541/au.162030341.15133179/v1","title":"EFFECT OF CENTRALLY AND PERIPHERALLY ACTING GABAB AGONISM ON THE COUGH REFLEX","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Respiratory and Cough-Related Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Manchester Biomedical Research Centre; Medical Research Council; National Institute for Health and Care Research; European Respiratory Society; AstraZeneca","keywords":"Medicine; Baclofen; Anesthesia; Reflex; Placebo; Cough reflex; Capsaicin; Crossover study; Peripheral; ED50; Internal medicine; Agonist; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006668637,0.000382081,0.001284005,0.0001362719,0.0001640111,0.0003212108,0.0002115942,0.0003617859,0.003982781],"category_scores_gemma":[0.0006600822,0.0001741968,0.0003475999,0.0001170346,0.0005193091,0.0002648682,0.0002345628,0.0008724835,0.000330722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001506843,"about_ca_system_score_gemma":0.0003019189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001413225,"about_ca_topic_score_gemma":0.0003847224,"domain_scores_codex":[0.9997033,0.0001259049,0.00002772467,0.00004901132,0.00003642886,0.00005747512],"domain_scores_gemma":[0.9994804,0.0002007543,0.0001181985,0.00003845934,0.0000353937,0.0001268218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.4915824,0.01013709,0.004846894,0.001829282,0.0004988188,0.0002484209,0.0001451059,0.0004181824,0.3988222,0.0001456124,0.0004048386,0.09092114],"study_design_scores_gemma":[0.03670603,0.8833386,0.02757462,0.00007989527,0.0005486981,0.0005394796,0.0001083168,0.0004856735,0.04933421,0.00007257569,0.00119051,0.00002144677],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973072,0.001886015,0.00009328347,0.00004532999,0.00003428194,0.000107405,0.00005873885,0.00001254759,0.0004552239],"genre_scores_gemma":[0.9982064,0.0008809269,0.0002372505,0.00006341706,0.00006880759,0.00009375867,0.00007804316,0.000003450522,0.0003679633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003982781,"threshold_uncertainty_score":0.01332372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03055640146019643,"score_gpt":0.3459812475069139,"score_spread":0.3154248460467175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}