{"id":"W4213380355","doi":"10.1016/j.humimm.2022.02.001","title":"Reducing number of laboratories performing complement dependent cytotoxicity crossmatching: Reasons and conclusions","year":2022,"lang":"en","type":"article","venue":"Human Immunology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Complement-dependent cytotoxicity; Human leukocyte antigen; Medicine; Histocompatibility; Antibody; Immunology; Histocompatibility Testing; Cytotoxicity; Antigen; Flow cytometry; Antibody-dependent cell-mediated cytotoxicity; Chemistry; Monoclonal antibody; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001181841,0.00009436558,0.000254761,0.00005223318,0.0006637644,0.000007610269,0.00005466906,0.00002618104,0.0009957309],"category_scores_gemma":[0.00001270379,0.00008607504,0.00003998567,0.00007882883,0.0001066222,0.0000356795,0.0001333342,0.0001732904,0.000003171876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008197701,"about_ca_system_score_gemma":0.00005550583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003433074,"about_ca_topic_score_gemma":0.00002047001,"domain_scores_codex":[0.9992287,0.00006539244,0.0002476283,0.0001575331,0.0001462127,0.0001545675],"domain_scores_gemma":[0.9995922,0.0000600442,0.0001045328,0.0001597812,0.00004717118,0.00003622758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002775407,0.0003867548,0.8357829,0.000166267,0.0005254462,0.0001172255,0.00652118,0.00001395493,0.1287824,0.02704514,0.00003079916,0.0003504089],"study_design_scores_gemma":[0.01000443,0.001694991,0.9374176,0.0002965955,0.0004312514,0.002234523,0.01081011,0.00002706168,0.03263729,0.001262177,0.002833907,0.0003501225],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979423,0.0002496183,0.00001629099,0.0001450173,0.0001039265,0.0002041333,0.00007650661,0.00002396178,0.001238272],"genre_scores_gemma":[0.9986759,0.00006622852,0.0004724482,0.0000736326,0.00001267776,0.00003709219,0.0001028375,0.00001086727,0.0005483538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1016346,"threshold_uncertainty_score":0.9999175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02902830884340341,"score_gpt":0.338539033015487,"score_spread":0.3095107241720836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}