{"id":"W4213395972","doi":"","title":"Ectoderm to mesoderm transition by downregulation of actomyosin contractility","year":2019,"lang":"en","type":"preprint","venue":"","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Ectoderm; Mesoderm; Transition (genetics); Contractility; Downregulation and upregulation; Cell biology; FGF and mesoderm formation; Chemistry; Embryo; Biology; Embryogenesis; Endocrinology; Biochemistry; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008726326,0.000337053,0.0002839362,0.0001919665,0.0001074189,0.0004490382,0.0002044132,0.0002349554,0.00195977],"category_scores_gemma":[0.0001078401,0.0001823972,0.0002002276,0.00009891022,0.0002300171,0.0001234952,0.0002886752,0.000607384,0.000647796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001599119,"about_ca_system_score_gemma":0.0001743123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003613233,"about_ca_topic_score_gemma":0.0005284225,"domain_scores_codex":[0.9998879,0.00001862707,0.000008547287,0.00002550758,0.0000326042,0.00002665883],"domain_scores_gemma":[0.9998995,0.00001895933,0.00002612364,0.00001663479,0.0000070796,0.00003179569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007342933,0.00001120975,0.00008335285,0.00002149979,0.000003180594,0.00003697868,0.000005511518,0.00004443019,0.9987237,0.0001170624,0.00004289144,0.000836605],"study_design_scores_gemma":[0.0000313693,0.0001214615,0.007199471,0.000005032887,0.00001158903,0.0001766811,0.00001311691,0.000964961,0.9875409,0.00007327311,0.003857785,0.000004365585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989704,0.001525883,0.003736213,0.0001649724,0.00006478576,0.00003127808,0.0003300967,0.0002493436,0.004193408],"genre_scores_gemma":[0.9920196,0.0008333196,0.001370145,0.00006641696,0.00001714951,0.00003555295,0.0003237638,0.00007096921,0.005263097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00195977,"threshold_uncertainty_score":0.006556094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00759141961992346,"score_gpt":0.2542528460629191,"score_spread":0.2466614264429957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}