{"id":"W4213413789","doi":"10.1136/bmjopen-2021-058850","title":"Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing liver resection: protocol for the haemorrhage during liver resection tranexamic acid (HeLiX) randomised controlled trial","year":2022,"lang":"en","type":"article","venue":"BMJ Open","topic":"Blood transfusion and management","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; McMaster University; Juravinski Hospital; Nova Scotia Health Authority; Dalhousie University; Queen's University; Sunnybrook Health Science Centre; Kelowna General Hospital; Foothills Medical Centre; Kingston General Hospital; University of Calgary; Western University; University of Toronto; University Health Network; Health Sciences Centre; St Joseph's Health Centre; University of British Columbia; Public Health Ontario; McGill University Health Centre","funders":"Arts and Humanities Research Council; Canadian Institutes of Health Research; National Cancer Institute; Physicians' Services Incorporated Foundation; Canadian Blood Services","keywords":"Medicine; Tranexamic acid; Perioperative; Blood transfusion; Clinical endpoint; Randomized controlled trial; Antifibrinolytic; Placebo; Surgery; Packed red blood cells; Anesthesia; Blood loss","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01595237,0.00505273,0.009428667,0.001262563,0.001929008,0.004126131,0.003164064,0.006581258,0.05604215],"category_scores_gemma":[0.02312666,0.00222035,0.005593069,0.002008185,0.00250457,0.002457528,0.001578878,0.006147909,0.008883006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003574235,"about_ca_system_score_gemma":0.01054106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003619042,"about_ca_topic_score_gemma":0.006983896,"domain_scores_codex":[0.989049,0.006665649,0.001183136,0.0009667624,0.001006154,0.001129259],"domain_scores_gemma":[0.9929879,0.001774117,0.0017243,0.0008360898,0.001450953,0.001226666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9598106,0.002286902,0.0002569735,0.01380354,0.002218258,0.00008848185,0.00015583,0.0005276396,0.0008914117,0.001283161,0.009694116,0.00898318],"study_design_scores_gemma":[0.9802505,0.007065092,0.0005720667,0.001402979,0.001010105,0.0000314271,0.00004105286,0.000531485,0.0002182387,0.0006878533,0.008143342,0.00004596826],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.008585321,0.001261825,0.001305198,0.0008360801,0.001253578,0.9801217,0.003905841,0.0002021377,0.002528197],"genre_scores_gemma":[0.01068457,0.0007482508,0.002405972,0.0006319864,0.0001788222,0.9825392,0.00066384,0.00001603218,0.002131349],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.05604215,"threshold_uncertainty_score":0.1874797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0702588538950857,"score_gpt":0.3658099373876162,"score_spread":0.2955510834925305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}