{"id":"W4213440197","doi":"10.1128/jvi.01903-21","title":"MicroRNA 122 Affects both the Initiation and the Maintenance of Hepatitis C Virus Infections","year":2021,"lang":"en","type":"article","venue":"Journal of Virology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Government of Canada; University of Saskatchewan","keywords":"Internal ribosome entry site; Replicon; Viral replication; Hepatitis C virus; NS2-3 protease; Virus; RNA; Untranslated region; Viral life cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003181417,0.0002606276,0.0002526873,0.0002246709,0.0002103308,0.0004660857,0.0001284949,0.0002519949,0.00125183],"category_scores_gemma":[0.0006581364,0.0001112649,0.0001969733,0.00009750578,0.0001592751,0.0002289171,0.000224938,0.000307364,0.000388104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002033048,"about_ca_system_score_gemma":0.0001662384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002275757,"about_ca_topic_score_gemma":0.0002805502,"domain_scores_codex":[0.9997279,0.00008020989,0.00003306371,0.00003994906,0.00007392559,0.00004500362],"domain_scores_gemma":[0.9997906,0.00006231589,0.00003747334,0.00002636194,0.0000386663,0.00004463126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001144699,0.00002329759,0.0005204677,0.00002502264,0.000003282155,0.00007734154,0.000009903645,0.00005287213,0.9958128,0.0001600744,0.00004381009,0.003156588],"study_design_scores_gemma":[0.00001604847,0.0004950319,0.01437368,0.000009300784,0.00002647637,0.0005256486,0.00003159404,0.001253753,0.9787608,0.0001702838,0.004326603,0.00001066023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851856,0.004446547,0.003629481,0.0001640252,0.0001284493,0.00002405849,0.0001399446,0.0001453481,0.006136522],"genre_scores_gemma":[0.9964858,0.0008692422,0.001203633,0.0000346876,0.00002239403,0.0000110729,0.00007553181,0.0000154504,0.001282124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00125183,"threshold_uncertainty_score":0.004187763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005124139093316023,"score_gpt":0.2295892017279544,"score_spread":0.2244650626346383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}