{"id":"W4213449388","doi":"10.2337/db21-1036","title":"Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796–2809","year":2022,"lang":"en","type":"letter","venue":"Diabetes","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nexen (Canada)","funders":"Novo Nordisk Fonden","keywords":"AMPK; Skeletal muscle; Endocrinology; Internal medicine; RAC1; Contraction (grammar); Diabetes mellitus; Chemistry; Medicine; Cell biology; Biology; Phosphorylation; Signal transduction; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004031984,0.001324494,0.001761591,0.0009977149,0.002636461,0.003209587,0.002486109,0.03658947,0.00590556],"category_scores_gemma":[0.01807282,0.0008665638,0.001645561,0.0007721352,0.00257457,0.003146344,0.001506771,0.03798664,0.0118221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003509108,"about_ca_system_score_gemma":0.00234319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004972413,"about_ca_topic_score_gemma":0.006598471,"domain_scores_codex":[0.9974666,0.0005423345,0.0003509684,0.0004653608,0.0008826968,0.0002920749],"domain_scores_gemma":[0.9937867,0.003197076,0.0003598407,0.0002400297,0.001603156,0.0008132524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007285784,0.00002467572,0.0001636185,0.0000422787,0.00001350941,0.000593757,0.00003396266,0.00002793087,0.0001125196,0.0005000159,0.9945286,0.003886341],"study_design_scores_gemma":[0.0002261356,0.0001291362,0.001571265,0.0002480248,0.00007451396,0.001657772,0.0001908199,0.0003890207,0.0005861183,0.005695478,0.9891164,0.0001152815],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003266766,0.001922654,0.0001655094,0.8903914,0.1053829,0.00002117617,0.0001514566,0.00007378871,0.001564482],"genre_scores_gemma":[0.001938732,0.001454859,0.0001591732,0.9041057,0.08618794,0.00005057478,0.00006207145,0.0000317525,0.006009124],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03658947,"threshold_uncertainty_score":0.02546048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004987365656664105,"score_gpt":0.2286354279503654,"score_spread":0.2236480622937013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}