{"id":"W4214531893","doi":"10.3389/fnins.2022.810148","title":"Longitudinal Assessment of Behaviour and Associated Bio-Markers Following Chronic Consumption of β-Sitosterol β-D-Glucoside in Rats: A Putative Model of Parkinson’s Disease","year":2022,"lang":"en","type":"article","venue":"Frontiers in Neuroscience","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"Weston Brain Institute","keywords":"Substantia nigra; Parkinsonism; Dopaminergic; Pathology; Tyrosine hydroxylase; Parkinson's disease; Medicine; Immunohistochemistry; Amyotrophic lateral sclerosis; Biology; Internal medicine; Disease; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003366492,0.000921032,0.0007668319,0.001001484,0.0004636218,0.0004526031,0.0003708593,0.0007287436,0.001024568],"category_scores_gemma":[0.0002378298,0.0003671943,0.000637838,0.000379314,0.0006281748,0.0005379861,0.0005316865,0.002113088,0.0005198509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005364995,"about_ca_system_score_gemma":0.0005442369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002620451,"about_ca_topic_score_gemma":0.006793898,"domain_scores_codex":[0.9997429,0.00002589111,0.0000162673,0.00007872646,0.00005350722,0.00008277005],"domain_scores_gemma":[0.9992931,0.00003205735,0.0001689996,0.00006629559,0.0001278697,0.0003116232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004950736,0.003685076,0.01404964,0.00007669901,0.00008252548,0.0002674899,0.0003312653,0.0001553465,0.971526,0.00005358346,0.0001953923,0.004626206],"study_design_scores_gemma":[0.0002945061,0.08265326,0.2872011,0.00004777088,0.0004494593,0.001020564,0.001201923,0.001673372,0.6222922,0.0002165081,0.002810518,0.0001388224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980229,0.0002567671,0.0005579955,0.00004619022,0.00001811612,0.00006735644,0.0006161069,0.00005269995,0.0003618232],"genre_scores_gemma":[0.9877965,0.0008089349,0.001568193,0.0001149289,0.00001627299,0.000367236,0.002358691,0.00002448533,0.006944838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002620451,"threshold_uncertainty_score":0.0052104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02667115867868037,"score_gpt":0.2981272461187827,"score_spread":0.2714560874401024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}