{"id":"W4214566820","doi":"10.1101/2022.02.25.481936","title":"Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"St Vincent's Hospital Melbourne; University of Toronto","keywords":"Biology; Thymocyte; T cell; CD8; Cell biology; Cellular differentiation; Immune system; Transcription factor; Progenitor cell; Immunology; Stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009050925,0.000292516,0.0001804,0.000383043,0.0002143066,0.0003382155,0.0001609853,0.0001703379,0.002411281],"category_scores_gemma":[0.0001210757,0.0001193333,0.0001578391,0.0001376577,0.0001120071,0.0001548143,0.0002301731,0.0005314747,0.0007086503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001816639,"about_ca_system_score_gemma":0.0001125609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003675151,"about_ca_topic_score_gemma":0.0008482469,"domain_scores_codex":[0.9998939,0.000006955327,0.000008898308,0.00004055055,0.00002059242,0.00002897932],"domain_scores_gemma":[0.9998437,0.00002479482,0.00004045998,0.00001547872,0.00002545921,0.00005008196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005487879,0.000006714774,0.0018837,0.00002462276,0.000002113734,0.00004278405,0.00003116363,0.00001851453,0.996879,0.00004694439,0.00001854553,0.0009909949],"study_design_scores_gemma":[0.00001246359,0.0002292148,0.1208049,0.00003138951,0.00003424597,0.001549753,0.0002291612,0.0005925189,0.8703068,0.0001787958,0.006018403,0.00001235839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993125,0.001174335,0.002369521,0.00002509835,0.00001089357,0.00002620772,0.0007509704,0.00004793483,0.002470113],"genre_scores_gemma":[0.9913166,0.0007440604,0.002246253,0.00009767966,0.00001229784,0.00004083631,0.001396291,0.00004945851,0.004096513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002411281,"threshold_uncertainty_score":0.008066535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441732791597808,"score_gpt":0.215713492004657,"score_spread":0.201296164088679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}