{"id":"W4214604880","doi":"10.1128/spectrum.02314-21","title":"Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen <i>Streptomyces</i> sp. 11-1-2","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Plant Disease Resistance and Genetics","field":"Agricultural and Biological Sciences","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Phytotoxin; Geldanamycin; Nigericin; Streptomyces; Pathogen; Biology; Streptomycetaceae; Phytotoxicity; Common scab; Microbiology; Botany; Toxin; Actinomycetales; Bacteria; Biochemistry; Genetics; Gene; Hsp90","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009699722,0.0005572137,0.0003090656,0.0002687705,0.0001232428,0.0002832826,0.0001415511,0.0004629084,0.0008698062],"category_scores_gemma":[0.000169851,0.0001248974,0.0002658174,0.0001966287,0.000237498,0.0001435373,0.0002359666,0.0004928678,0.0003924514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002256987,"about_ca_system_score_gemma":0.0001505637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003782589,"about_ca_topic_score_gemma":0.0005692987,"domain_scores_codex":[0.9998104,0.00004759397,0.00001897041,0.00004313145,0.00004272322,0.00003726272],"domain_scores_gemma":[0.9997699,0.00004201389,0.00008064401,0.00002158742,0.00001715606,0.00006868433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008958217,0.00001803852,0.0003539792,0.00007551104,0.000005331546,0.0001596023,0.000006299026,0.00004555117,0.9971159,0.00005346824,0.00004517936,0.002031587],"study_design_scores_gemma":[0.0000183044,0.0006293562,0.01201219,0.00001446736,0.00001234444,0.00118855,0.00004255529,0.0001491098,0.981628,0.0001080182,0.004186492,0.00001080368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620236,0.01571001,0.008320316,0.0003537981,0.0001262039,0.0002180593,0.001713275,0.000412298,0.01112258],"genre_scores_gemma":[0.9907899,0.00230872,0.004551098,0.0001182703,0.00001358442,0.00004818924,0.0006950985,0.0000141978,0.001460976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008698062,"threshold_uncertainty_score":0.00290978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00832892311118026,"score_gpt":0.1757218167551884,"score_spread":0.1673928936440081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}