{"id":"W4214604880","doi":"10.1128/spectrum.02314-21","title":"Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen <i>Streptomyces</i> sp. 11-1-2","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Plant Disease Resistance and Genetics","field":"Agricultural and Biological Sciences","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Phytotoxin; Geldanamycin; Nigericin; Streptomyces; Pathogen; Biology; Streptomycetaceae; Phytotoxicity; Common scab; Microbiology; Botany; Toxin; Actinomycetales; Bacteria; Biochemistry; Genetics; Gene; Hsp90","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002418967,0.0002172666,0.0003060191,0.00001401034,0.000646118,0.00004463525,0.0003673502,0.00006345037,0.0005568331],"category_scores_gemma":[0.0000158046,0.0000839127,0.00009471618,0.0002675687,0.000140514,0.00002972574,0.0002083278,0.0001847519,0.00001581486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000289029,"about_ca_system_score_gemma":0.00001398074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008901179,"about_ca_topic_score_gemma":0.0009496575,"domain_scores_codex":[0.9984322,0.0002804032,0.0002278385,0.0004997256,0.00009214677,0.0004676877],"domain_scores_gemma":[0.9995124,0.0001243906,0.0001508519,0.0001215788,0.00001235572,0.00007839577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006979211,0.00007179302,0.01851125,0.000003930481,0.00002938296,0.00002233058,0.00003502647,0.000001149254,0.9507552,0.00005221325,0.0300845,0.0003633844],"study_design_scores_gemma":[0.0003176509,0.0001531444,0.03390873,0.000006334372,0.00005026094,0.0001670416,0.000600578,0.00000379417,0.2495311,0.0003182149,0.7145936,0.0003495756],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782401,0.008206839,2.630908e-7,0.006800328,0.0001813643,0.0003705075,0.006061011,0.00005439595,0.00008517792],"genre_scores_gemma":[0.9956392,0.0004721446,0.000009025165,0.001978522,0.0002801518,0.00006660735,0.001065455,0.000002537314,0.0004863629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7012241,"threshold_uncertainty_score":0.6096932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00832892311118026,"score_gpt":0.1757218167551884,"score_spread":0.1673928936440081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}