{"id":"W4214617427","doi":"10.3390/microorganisms10030535","title":"Persistent Cutaneous Leishmania major Infection Promotes Infection-Adapted Myelopoiesis","year":2022,"lang":"en","type":"article","venue":"Microorganisms","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Myelopoiesis; Bone marrow; Haematopoiesis; Immunology; Myeloid; Spleen; Biology; Leishmania major; Leishmania mexicana; Progenitor cell; Immune system; Chemokine; Inflammation; Monocyte; Leishmania; Stem cell; Cell biology; Parasite hosting","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003406562,0.0003085195,0.0004611006,0.0003796301,0.001214715,0.00008000105,0.0001415178,0.00008855464,0.003887307],"category_scores_gemma":[0.0003087544,0.0003071317,0.0002998596,0.0008355587,0.0001432951,0.0001165103,0.0005012585,0.000663551,0.0003721602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000904936,"about_ca_system_score_gemma":0.0002191166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0013021,"about_ca_topic_score_gemma":0.0002485244,"domain_scores_codex":[0.9974799,0.0001790477,0.0003919348,0.0005891392,0.0007591692,0.0006008242],"domain_scores_gemma":[0.9989123,0.00009398458,0.0001311064,0.0003934708,0.0002728331,0.0001962432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007079488,0.001861232,0.22407,0.0004548254,0.001792234,0.0009167664,0.00409436,0.00006198856,0.7302607,0.0001811239,0.02619904,0.009399793],"study_design_scores_gemma":[0.008224353,0.01108288,0.3618048,0.0002444372,0.001758109,0.01991013,0.004091101,0.0003668496,0.3454231,0.0003343419,0.2447814,0.0019785],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908521,0.0005208565,0.0001109468,0.00331245,0.0004437551,0.001091073,0.00002993673,0.00043618,0.003202765],"genre_scores_gemma":[0.9905446,0.0001489082,0.0003906986,0.0004711617,0.0002131548,0.0002165407,0.00007665336,0.00009444211,0.007843903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3848376,"threshold_uncertainty_score":0.9999381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01933175820503274,"score_gpt":0.2608394644087252,"score_spread":0.2415077062036924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}