{"id":"W4214644529","doi":"10.1021/acsbiomaterials.1c01399","title":"A Three-Dimensional Printable Hydrogel Formulation for the Local Delivery of Therapeutic Nanoparticles to Cervical Cancer","year":2022,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Poloxamer; In vivo; HeLa; Nanoparticle; Materials science; Ex vivo; Biomedical engineering; Drug delivery; Biophysics; Colloidal gold; Self-healing hydrogels; Nanotechnology; Chemistry; In vitro; Polymer; Medicine; Polymer chemistry; Biochemistry; Copolymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001154493,0.0003223996,0.000107138,0.0001730138,0.0001086112,0.0001555494,0.0001692845,0.0003009197,0.0006883391],"category_scores_gemma":[0.0001117857,0.0001314387,0.0002373378,0.00007997613,0.0001065395,0.0001906642,0.0001382375,0.0002673767,0.0002493768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002870771,"about_ca_system_score_gemma":0.0001566222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005074285,"about_ca_topic_score_gemma":0.001078231,"domain_scores_codex":[0.99994,0.000006805838,0.000005037048,0.00001582904,0.00002163019,0.00001068508],"domain_scores_gemma":[0.9999421,0.00001168085,0.00002303646,0.00000445342,0.000008194851,0.00001061454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001415503,0.0000110514,0.00002222473,0.00005086569,0.000002702754,0.00004331014,0.000008270017,0.0001313797,0.9967583,0.00005849281,0.00004835753,0.002850882],"study_design_scores_gemma":[0.000009561769,0.0001937677,0.000487033,0.000007121131,0.00001212035,0.0002482384,0.000005613789,0.001389774,0.994275,0.00001785212,0.003344465,0.000009501248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9020206,0.01195933,0.07537352,0.0004912656,0.0002743515,0.00029104,0.0007275823,0.0005244263,0.008337971],"genre_scores_gemma":[0.9635614,0.002582274,0.02840797,0.000179911,0.00002656481,0.0001290033,0.0002328946,0.00003981215,0.004840252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006883391,"threshold_uncertainty_score":0.002302766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0693891675110817,"score_gpt":0.3717742904359234,"score_spread":0.3023851229248417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}