{"id":"W4214688240","doi":"10.1101/2022.02.25.481661","title":"Thermal regime during parental sexual maturation, but not during offspring rearing, modulates DNA methylation in brook charr ( <i>Salvelinus fontinalis</i> )","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Rimouski; Université de Sherbrooke; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Université du Québec à Rimouski; Université Laval","keywords":"Salvelinus; Offspring; Biology; Epigenetics; DNA methylation; Genetics; Zoology; Ecology; Gene; Pregnancy; Trout; Gene expression; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156818,0.0001276923,0.0001303558,0.0001262506,0.0001372186,0.0002139549,0.0001056895,0.0001169868,0.001267009],"category_scores_gemma":[0.00011776,0.00008790947,0.0001212629,0.00008321203,0.0001325731,0.00009872685,0.0002228005,0.0002162793,0.0001817074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002118858,"about_ca_system_score_gemma":0.0001104354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002166808,"about_ca_topic_score_gemma":0.005077327,"domain_scores_codex":[0.9999238,0.00001013818,0.000003953587,0.00003939211,0.00001100274,0.00001177601],"domain_scores_gemma":[0.9998758,0.00001648055,0.00005246801,0.00001308363,0.00001532057,0.00002676782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002215183,0.00001779119,0.0150829,0.00001434206,0.00001430394,0.0000230696,0.00007201116,0.00003347278,0.983051,0.00001747235,0.00004328409,0.001408832],"study_design_scores_gemma":[0.00000921576,0.0002485164,0.9093801,0.000005626131,0.00002930274,0.0001144876,0.0001406627,0.0004453471,0.08906616,0.00002866036,0.0005238381,0.00000805124],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994171,0.00006607582,0.0001709524,0.00001225336,0.000002707233,0.000001413837,0.0001420328,0.000008423912,0.0001790297],"genre_scores_gemma":[0.9981645,0.00004743199,0.0002479095,0.00002480028,0.000002285306,0.000008837642,0.0003724674,0.00001256667,0.001119172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002166808,"threshold_uncertainty_score":0.004308403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021531385069855,"score_gpt":0.2215099649122597,"score_spread":0.2112946510615611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}