{"id":"W4214751185","doi":"10.3390/genes13030423","title":"Conserved Molecular Signatures in the Spike, Nucleocapsid, and Polymerase Proteins Specific for the Genus Betacoronavirus and Its Different Subgenera","year":2022,"lang":"en","type":"article","venue":"Genes","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Subgenus; Betacoronavirus; Coronavirus; Genetics; Genus; Virology; Evolutionary biology; Zoology; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031982,0.0001500117,0.0001865251,0.00007791459,0.0003045178,0.00005137024,0.0001927822,0.00004430191,0.00002632579],"category_scores_gemma":[0.00003438252,0.00008635381,0.00006277925,0.0001494269,0.00008927087,0.00002127981,0.0001477812,0.0002466445,0.000001275384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002882526,"about_ca_system_score_gemma":0.00006646027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001471659,"about_ca_topic_score_gemma":0.0001017241,"domain_scores_codex":[0.998789,0.0001482262,0.0001521897,0.0002864801,0.0003459158,0.0002782363],"domain_scores_gemma":[0.9994121,0.00021181,0.00003516367,0.0002799538,0.00003206858,0.00002889959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000660836,0.0001686154,0.007361956,0.00009277912,0.00007133154,0.0002059153,0.0007885027,0.000005581588,0.9629406,0.0008129797,0.0004181044,0.02647284],"study_design_scores_gemma":[0.003174667,0.0006955225,0.03222651,0.00001914859,0.00008994122,0.00009548441,0.001079551,0.001247546,0.7561499,0.0002580359,0.2047258,0.0002379448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9027872,0.09297264,0.00002619481,0.002447976,0.00006847084,0.00159627,0.00004143055,0.0000139826,0.00004582651],"genre_scores_gemma":[0.9842777,0.0001739235,0.00002511454,0.01460277,0.0001151605,0.0007457999,0.000005220316,0.0000231854,0.0000311177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2067907,"threshold_uncertainty_score":0.3521406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04816040344761503,"score_gpt":0.3119151313005125,"score_spread":0.2637547278528975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}