{"id":"W4214756507","doi":"10.1139/cjm-46-3-283","title":"Oral immunization of mice with a glycoconjugate vaccine containing the O157 antigen of <i>Escherichia coli</i> O157:H7 admixed with cholera toxin fails to elicit protection against subsequent colonization by the pathogen","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Cholera toxin; Microbiology; Antigen; Escherichia coli; Cholera vaccine; Glycoconjugate; Cholera; Immunization; Biology; Toxin; Vibrio cholerae; Virology; Immunology; Bacteria; Gene; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004900605,0.00135622,0.001403079,0.0007087384,0.000448013,0.0006415766,0.0006900109,0.001902166,0.002061908],"category_scores_gemma":[0.0003947848,0.0006068758,0.00085622,0.0003338108,0.0008431014,0.0007890098,0.0002995581,0.003550459,0.0009520656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006939641,"about_ca_system_score_gemma":0.0009801119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002455787,"about_ca_topic_score_gemma":0.002458254,"domain_scores_codex":[0.9994893,0.00003848148,0.00002813822,0.0001318611,0.0001215035,0.000190729],"domain_scores_gemma":[0.9992204,0.0001238705,0.0001999602,0.0001134832,0.00007793394,0.0002643372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002670747,0.00115886,0.0004248628,0.0000916407,0.00004257776,0.000125361,0.00007378214,0.0002213845,0.9927689,0.0002783816,0.0002613979,0.001882146],"study_design_scores_gemma":[0.0004997474,0.01982377,0.006487027,0.0000555274,0.0001524499,0.0004791091,0.0001259624,0.001643781,0.9678789,0.0002775695,0.002544727,0.00003149325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932218,0.0007576589,0.001713973,0.0004143181,0.0004234364,0.0001092853,0.000563814,0.0002335871,0.002562206],"genre_scores_gemma":[0.9837923,0.001005765,0.00182737,0.0005269183,0.0001175587,0.0001156386,0.001903666,0.0001005983,0.01061017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002455787,"threshold_uncertainty_score":0.006897748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007843698020358315,"score_gpt":0.2133024032129253,"score_spread":0.205458705192567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}