{"id":"W4214820217","doi":"10.1002/9783527815562.mme0020","title":"Novel Polymer Systems for Gene Therapy","year":2022,"lang":"en","type":"other","venue":"","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Gene delivery; Genetic enhancement; Nanotechnology; Nanocapsules; Biocompatibility; Cytotoxicity; Biocompatible material; Chemistry; Nanoparticle; Materials science; Gene; Biochemistry; Biomedical engineering; Medicine; In vitro; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002256017,0.000670303,0.0002315003,0.0006182592,0.0003330358,0.0005526488,0.0003427518,0.000613702,0.008389382],"category_scores_gemma":[0.000181039,0.0002026064,0.0002443991,0.0003668963,0.0003137702,0.0009296223,0.0004852375,0.0008243353,0.003330256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004253735,"about_ca_system_score_gemma":0.0002131538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000169762,"about_ca_topic_score_gemma":0.000195426,"domain_scores_codex":[0.9998726,0.00002255331,0.000007782912,0.00004060375,0.00003771311,0.00001890167],"domain_scores_gemma":[0.9999399,0.00001811454,0.00001606896,0.000005676558,0.00001075597,0.000009488456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001483051,0.0001927159,0.0001385008,0.002145536,0.00003719935,0.0006164507,0.0001801958,0.002289807,0.7035311,0.09098776,0.008353004,0.1913793],"study_design_scores_gemma":[0.00006880174,0.000440619,0.0002050228,0.0001255883,0.00003082984,0.0006713232,0.00002402102,0.003163457,0.5038667,0.005722094,0.4856443,0.00003723921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.1121607,0.3379496,0.275572,0.003420716,0.004177752,0.001030235,0.0007659337,0.001929153,0.2629939],"genre_scores_gemma":[0.5796323,0.1523223,0.1061026,0.001954738,0.0007383603,0.001188254,0.000645823,0.0002721551,0.1571434],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.008389382,"threshold_uncertainty_score":0.02806526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02005257668509826,"score_gpt":0.2556985547443383,"score_spread":0.23564597805924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}