{"id":"W4214842935","doi":"10.51731/cjht.2022.274","title":"Emerging Drugs for Amyotrophic Lateral Sclerosis","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Amyotrophic lateral sclerosis; Riluzole; Medicine; Drug development; Intensive care medicine; Disease; Drug; Pharmacology; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00113306,0.0001409616,0.0004853618,0.000981696,0.0008861818,0.00003447181,0.0004489727,0.00008419665,0.0002071734],"category_scores_gemma":[0.0003379603,0.0001225922,0.0001756475,0.0005568538,0.000185914,0.0001007619,0.00008055401,0.0008830771,0.000003993627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001451643,"about_ca_system_score_gemma":0.003150242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003034153,"about_ca_topic_score_gemma":0.0002526857,"domain_scores_codex":[0.9978471,0.00008865896,0.0006471516,0.000187339,0.0004006248,0.0008291217],"domain_scores_gemma":[0.9988819,0.00005701075,0.000340679,0.0002837135,0.0002303496,0.0002063767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003058594,0.00007865154,0.01337412,0.000361444,0.0001933351,0.0002510119,0.001624017,0.0002517301,0.002274595,0.001538424,0.03248437,0.9472625],"study_design_scores_gemma":[0.005984351,0.007596993,0.1218189,0.0008234046,0.00008115729,0.001380388,0.01100957,0.0005214806,0.000767182,0.00907117,0.8403583,0.0005871551],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8092947,0.01936878,0.0001606337,0.1697422,0.0005007501,0.0006837682,0.00005894966,0.0001135861,0.00007662161],"genre_scores_gemma":[0.9969216,0.0003716391,0.001169773,0.0011995,0.00003234424,0.00006287583,0.000007150968,0.00003275422,0.0002023396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9466753,"threshold_uncertainty_score":0.6815884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05475330339128814,"score_gpt":0.3152211238897473,"score_spread":0.2604678204984591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}