{"id":"W4214851245","doi":"10.1101/2022.03.01.481631","title":"Deletion of <i>proU</i> suppresses <i>proQ</i> phenotypes in <i>Escherichia coli</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Escherichia coli; Operon; Biology; Phenotype; Osmolyte; Suppressor mutation; Cell biology; Gene; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002175031,0.0006223482,0.000329079,0.0003689007,0.0001991495,0.0004478295,0.0004238104,0.0003448765,0.00111813],"category_scores_gemma":[0.0003088898,0.0002906916,0.0003590192,0.0002411624,0.0003845046,0.0001394067,0.0004323371,0.0006962178,0.000940476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003415486,"about_ca_system_score_gemma":0.0002807343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001320708,"about_ca_topic_score_gemma":0.001236932,"domain_scores_codex":[0.999563,0.000104408,0.0000562298,0.00005745615,0.0001319769,0.00008686051],"domain_scores_gemma":[0.9993458,0.0001489495,0.0002074064,0.0001008066,0.00005689942,0.0001400712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004552612,0.0000323356,0.0001478287,0.00001336174,0.00000340674,0.00004796142,0.00001309051,0.00005995886,0.9991235,0.00007601328,0.00002570453,0.0004112854],"study_design_scores_gemma":[0.00001071921,0.0001281883,0.004278121,0.000008974554,0.00001100515,0.0002736156,0.00004801876,0.001077007,0.9926339,0.00002342163,0.001497219,0.000009879394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913642,0.0002422974,0.006054325,0.00008138189,0.00002802683,0.00005432496,0.0007627967,0.0001865721,0.001226107],"genre_scores_gemma":[0.9919857,0.0001344424,0.003998872,0.00007292823,0.00001119524,0.00005702537,0.001376016,0.0001955858,0.002168154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320708,"threshold_uncertainty_score":0.003740489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007827254350646396,"score_gpt":0.206115288501547,"score_spread":0.1982880341509006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}