{"id":"W4214886362","doi":"10.1038/s41541-022-00449-1","title":"Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Global Health Innovative Technology Fund","keywords":"Leishmania mexicana; Amastigote; Leishmania; Cutaneous leishmaniasis; Leishmaniasis; Biology; Leishmania major; Immunology; Immunogenicity; Cytokine; Leishmania tropica; Virology; Immune system; Parasite hosting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008966198,0.0002352206,0.0001718048,0.000202061,0.0001230051,0.0002718362,0.0001928798,0.000313854,0.002125398],"category_scores_gemma":[0.00008296618,0.00009947188,0.0001461062,0.00008610741,0.0002023875,0.0001270854,0.0001333962,0.0005149755,0.0003271808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002259317,"about_ca_system_score_gemma":0.0001077228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005445277,"about_ca_topic_score_gemma":0.0005555059,"domain_scores_codex":[0.9999161,0.00001465778,0.00000787985,0.00002038691,0.00001831687,0.00002265892],"domain_scores_gemma":[0.9998965,0.00001222269,0.00003349827,0.00001152528,0.00001294428,0.00003322409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000221932,0.00007030382,0.0002287248,0.00004303722,0.00000640108,0.0000366639,0.000009712068,0.00004259891,0.9983541,0.00004618206,0.00008968871,0.0008506739],"study_design_scores_gemma":[0.0001494462,0.002559246,0.02171579,0.00003310924,0.00007163705,0.0009420784,0.0001902887,0.001827889,0.9615197,0.00008407181,0.01089148,0.00001530285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969845,0.0004792019,0.000839028,0.000136405,0.00002919019,0.00002604723,0.0005270361,0.00006794345,0.0009105],"genre_scores_gemma":[0.9955279,0.0002640862,0.0005453887,0.00006604801,0.000007216642,0.00002872582,0.0006498953,0.00001444742,0.002896209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002125398,"threshold_uncertainty_score":0.007110238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03637937889199591,"score_gpt":0.2797422591567296,"score_spread":0.2433628802647337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}