{"id":"W4214900386","doi":"10.1093/ecco-jcc/jjac030","title":"Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through 3 Years: UNIFI Long-term Extension","year":2022,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Calgary","funders":"Janssen Research and Development","keywords":"Medicine; Ustekinumab; Internal medicine; Adverse effect; Colonoscopy; Ulcerative colitis; Maintenance therapy; Placebo; Clinical endpoint; Intention-to-treat analysis; Randomized controlled trial; Gastroenterology; Surgery; Colorectal cancer; Adalimumab; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002307883,0.00009623369,0.000196243,0.00002955259,0.0001227013,0.00002022342,0.00009106693,0.0000468595,0.00004193872],"category_scores_gemma":[0.00006466848,0.00009346553,0.00008678967,0.00003511935,0.0001207809,0.00001186833,0.0001072478,0.00009012147,1.357446e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002644752,"about_ca_system_score_gemma":0.000130347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005582042,"about_ca_topic_score_gemma":0.00001514713,"domain_scores_codex":[0.9991415,0.00008721086,0.0003219901,0.0001498176,0.0001390836,0.0001604295],"domain_scores_gemma":[0.9992636,0.00002838884,0.0002818611,0.0001238458,0.0002204321,0.00008180729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6244388,0.002879395,0.0383713,0.002617374,0.003214308,0.01228267,0.01006842,0.001136367,0.05587717,0.04107663,0.06227058,0.145767],"study_design_scores_gemma":[0.003131943,0.0007145989,0.9819195,0.0000627265,0.00004965292,0.0003915576,0.0002511955,0.00001010494,0.001161203,0.000370824,0.01182202,0.0001146405],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980759,0.0006343606,0.0004643186,0.00009025109,0.0001286971,0.000266985,0.0001822651,0.00000162195,0.0001556212],"genre_scores_gemma":[0.9984096,0.0005969984,0.0003188495,0.0001716914,0.0001400528,0.00001205733,0.00001757692,0.00001404255,0.0003191151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9435483,"threshold_uncertainty_score":0.3811414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019832370868857,"score_gpt":0.2592584887982918,"score_spread":0.2490601650896032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}