{"id":"W4214900386","doi":"10.1093/ecco-jcc/jjac030","title":"Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through 3 Years: UNIFI Long-term Extension","year":2022,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Calgary","funders":"Janssen Research and Development","keywords":"Medicine; Ustekinumab; Internal medicine; Adverse effect; Colonoscopy; Ulcerative colitis; Maintenance therapy; Placebo; Clinical endpoint; Intention-to-treat analysis; Randomized controlled trial; Gastroenterology; Surgery; Colorectal cancer; Adalimumab; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003456352,0.0004565219,0.001285106,0.0003075439,0.0003331168,0.0004888566,0.000557363,0.0009904872,0.002290621],"category_scores_gemma":[0.001562175,0.0002269483,0.001505411,0.0003125973,0.0004846081,0.0006384727,0.0004763651,0.001597041,0.0003369187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004508929,"about_ca_system_score_gemma":0.0004728303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005109987,"about_ca_topic_score_gemma":0.001445353,"domain_scores_codex":[0.9990203,0.0004748406,0.00009760007,0.0001046086,0.0001558845,0.0001466132],"domain_scores_gemma":[0.9972599,0.0005708059,0.001221978,0.0002249105,0.0001387631,0.0005836377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.672065,0.01475284,0.04825427,0.001370481,0.002390207,0.0001764078,0.0002602327,0.0006886934,0.01167508,0.0001002604,0.001359014,0.2469075],"study_design_scores_gemma":[0.1978377,0.5463865,0.2455452,0.0003029358,0.002796587,0.0006219185,0.00008773874,0.000731167,0.002836485,0.0001113983,0.002691802,0.0000506687],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881051,0.01054397,0.0001552725,0.0001347899,0.0000393765,0.0001685811,0.0001924946,0.00002308886,0.0006375187],"genre_scores_gemma":[0.9967493,0.001686119,0.0002217708,0.0001936331,0.000107568,0.000170317,0.0003397919,0.000003398421,0.0005282201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003456352,"threshold_uncertainty_score":0.01827919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019832370868857,"score_gpt":0.2592584887982918,"score_spread":0.2490601650896032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}