{"id":"W4214904596","doi":"10.1093/ajhp/zxac066","title":"An updated vancomycin dosing protocol for initiating therapy in patients undergoing intermittent high-flux hemodialysis","year":2022,"lang":"en","type":"article","venue":"American Journal of Health-System Pharmacy","topic":"Dialysis and Renal Disease Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Dosing; Medicine; Loading dose; Vancomycin; Hemodialysis; Maintenance dose; Dialysis; Population; Interquartile range; Pharmacokinetics; Anesthesia; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001925437,0.0002175935,0.0009677094,0.0006368395,0.0003008773,0.00004692872,0.0002411222,0.0000096955,0.0001187482],"category_scores_gemma":[0.0000259008,0.0001769242,0.0002842071,0.0007074037,0.00003872732,0.0001985831,0.00006675031,0.0003098062,0.00000131138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001041649,"about_ca_system_score_gemma":0.0005549183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002766565,"about_ca_topic_score_gemma":0.000006310107,"domain_scores_codex":[0.9959348,0.001083076,0.001605821,0.0002774308,0.000679309,0.0004195832],"domain_scores_gemma":[0.9970405,0.0001029517,0.002078696,0.0002272288,0.0002405646,0.0003100884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007410384,0.003013468,0.09961765,0.0007751344,0.0006832522,0.00009132174,0.001498324,0.002779311,0.0004014738,0.00004229353,0.002343328,0.8813441],"study_design_scores_gemma":[0.2865788,0.08543903,0.3694437,0.006312185,0.001487537,0.0003161549,0.04705535,0.03082532,0.002478727,0.0001161127,0.1675133,0.002433741],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9463105,0.00004706845,0.001670573,0.004298537,0.0003872815,0.04709191,0.00002731225,0.00004288798,0.0001239503],"genre_scores_gemma":[0.9822019,0.000005597065,0.001218343,0.002391749,0.000196901,0.0138724,0.00005816753,0.00004631833,0.000008597184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8789103,"threshold_uncertainty_score":0.7214758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03319856768631702,"score_gpt":0.3682322874415084,"score_spread":0.3350337197551914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}