{"id":"W4214904608","doi":"10.1016/j.biopsych.2021.12.008","title":"Reply to: Crossing the “Birth Border” for Epigenetic Effects","year":2022,"lang":"en","type":"letter","venue":"Biological Psychiatry","topic":"Birth, Development, and Health","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research; University of British Columbia; McGill University; Douglas Mental Health University Institute","funders":"Behavioural Science institute, Radboud University; National Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Agency for Science, Technology and Research; Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University; Canadian Institutes of Health Research; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh; McGill University; Jacobs Foundation; Ludmer Centre for Neuroinformatics and Mental Health; Canada First Research Excellence Fund; National University of Singapore; Radboud Universiteit; Koninklijke Nederlandse Akademie van Wetenschappen; Universiteit Leiden; Brain and Behavior Research Foundation; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Harvard University; JPB Foundation; Singapore Institute for Clinical Sciences; Hope for Depression Research Foundation; Medical Research Council; Medical Research Council Canada; Radboud Universitair Medisch Centrum; Fonds de Recherche du Québec - Santé; Child Study Center, Yale School of Medicine; Yale University; R. Howard Webster Foundation","keywords":"Scopus; Epigenetics; Mental health; Anxiety; Medicine; Psychiatry; Psychoanalysis; Psychology; MEDLINE; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007270982,0.001259476,0.002476073,0.001000535,0.008856262,0.005537438,0.002630971,0.09877934,0.008015087],"category_scores_gemma":[0.03504144,0.001377439,0.001687073,0.0009629779,0.005822259,0.006539717,0.004007574,0.09374169,0.007356624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005133987,"about_ca_system_score_gemma":0.009558821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01481663,"about_ca_topic_score_gemma":0.02139092,"domain_scores_codex":[0.9955351,0.001330014,0.0006303341,0.0006998037,0.001094916,0.0007097868],"domain_scores_gemma":[0.9858431,0.008499786,0.0008486377,0.0004032896,0.002022985,0.002382222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005913516,0.00002442131,0.000451872,0.00004724884,0.00001913964,0.0007402446,0.0002794985,0.00003245991,0.0001246233,0.002406874,0.9923918,0.003422705],"study_design_scores_gemma":[0.0001805574,0.00007372109,0.001813829,0.0005201458,0.00005698159,0.00108352,0.001520979,0.000309331,0.0002225168,0.01270096,0.9813778,0.000139632],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001083726,0.0005711521,0.00003493874,0.9886693,0.0100078,0.000005931206,0.0000316625,0.000009029651,0.0005618151],"genre_scores_gemma":[0.0006301784,0.0002400451,0.00006132939,0.9858209,0.01126496,0.00001816075,0.000009837371,0.00001086215,0.001943882],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.09877934,"threshold_uncertainty_score":0.03845304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03829139904175011,"score_gpt":0.3414512813794947,"score_spread":0.3031598823377445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}