{"id":"W4214944932","doi":"10.2196/33893","title":"Characteristics and Outcomes of Clinical Trials on Gene Therapy in Noncongenital Cardiovascular Diseases: Cross-sectional Study of Three Clinical Trial Registries","year":2022,"lang":"en","type":"article","venue":"JMIR Formative Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Clinical trial; Coronary artery disease; Placebo; Disease; Internal medicine; Randomized controlled trial; Clinical research; Physical therapy; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.07203602,0.0006059677,0.003285128,0.008769404,0.001097542,0.004210658,0.001714339,0.00161388,0.003192278],"category_scores_gemma":[0.200637,0.0007013354,0.003559208,0.01936835,0.001163064,0.003419403,0.002850028,0.001306766,0.0006350608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001270326,"about_ca_system_score_gemma":0.003028934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001476543,"about_ca_topic_score_gemma":0.001585108,"domain_scores_codex":[0.869248,0.04315563,0.06390414,0.008294429,0.01332941,0.002068475],"domain_scores_gemma":[0.5369732,0.178863,0.2420485,0.01652301,0.02123164,0.004360547],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004319843,0.0001783442,0.9717258,0.005284506,0.005366637,0.0001297112,0.0006374498,0.0002578039,0.0002134422,0.0004116945,0.001754834,0.009719958],"study_design_scores_gemma":[0.001410192,0.001101551,0.9799184,0.002892565,0.004725384,0.001043582,0.001241951,0.0004631369,0.0002532196,0.0004315622,0.006422686,0.00009569683],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8916251,0.05903892,0.002823598,0.00108904,0.00009917592,0.004253934,0.03528425,0.00009504476,0.005690968],"genre_scores_gemma":[0.9720814,0.007574899,0.001825233,0.000683617,0.00009750411,0.005479604,0.01184657,0.00006351609,0.0003476822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9967149,"threshold_uncertainty_score":0.3809674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.283239197637293,"score_gpt":0.5410514428735747,"score_spread":0.2578122452362816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}