{"id":"W4220653821","doi":"10.1002/chem.202200764","title":"Organic Base Enabled Nickel‐Catalyzed Mono‐α‐Arylation of Feedstock Solvents","year":2022,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Catalysis; Chemistry; Acetone; Electrophile; Aryl; Organic chemistry; Phenol; Base (topology); Raw material; Halide; Nickel; Organic synthesis; Organic base; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001391814,0.0002582306,0.0002998997,0.00007284922,0.0004919704,0.00006749706,0.0006332474,0.00004252883,0.05548699],"category_scores_gemma":[0.0005323493,0.000294192,0.0002451916,0.0003982731,0.00007748896,0.0001449636,0.0004123492,0.0007780337,0.00005946941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003736674,"about_ca_system_score_gemma":0.0002863317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003125684,"about_ca_topic_score_gemma":1.474824e-7,"domain_scores_codex":[0.9975,0.0001990067,0.0008775945,0.0003753551,0.0007232968,0.0003247269],"domain_scores_gemma":[0.9980151,0.0001146938,0.0008155153,0.0005728767,0.0002273798,0.0002544084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000148391,0.0002004318,0.0008596532,0.0001406499,0.0001084803,0.0001100938,0.0002198961,0.0008082985,0.991283,0.000004984215,0.004729339,0.001386787],"study_design_scores_gemma":[0.004954087,0.00004552974,0.0006636453,0.0001142093,0.0002383947,0.003001832,0.001365738,0.006050406,0.9401273,0.0002020338,0.04252214,0.000714688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733545,0.0002761068,0.006796007,0.0001714624,0.0003026456,0.00006765964,0.00008875795,0.00009940107,0.01884353],"genre_scores_gemma":[0.9777318,0.00002798127,0.001618959,0.00007505633,0.0006892493,0.00000983862,0.0005395138,0.0001306276,0.01917697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05542752,"threshold_uncertainty_score":0.999951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02169475281458691,"score_gpt":0.2432122951459463,"score_spread":0.2215175423313593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}