{"id":"W4220660249","doi":"10.1016/j.exphem.2022.03.010","title":"Single-cell analysis of cultured bone marrow stromal cells reveals high similarity to fibroblasts in situ","year":2022,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; Oncode Institute; MPN Stichting; Bundesministerium für Bildung und Forschung; Westfälische Wilhelms-Universität Münster; Deutsche Forschungsgemeinschaft; Cancer Couch Foundation; International Growth Centre; KWF Kankerbestrijding; European Hematology Association; MPN Research Foundation","keywords":"Stromal cell; In situ; Bone marrow; Cell; Similarity (geometry); Cell biology; Biology; Chemistry; Pathology; Molecular biology; Cancer research; Medicine; Immunology; Computer science; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001343004,0.0002437759,0.0002096331,0.0004211682,0.0002477279,0.0003956414,0.0001329808,0.0002598401,0.001269014],"category_scores_gemma":[0.0001226105,0.0001273858,0.000251326,0.0003287503,0.0001979376,0.0001373721,0.0001779099,0.0003540785,0.0007885754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001243319,"about_ca_system_score_gemma":0.0001924832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006155705,"about_ca_topic_score_gemma":0.00145168,"domain_scores_codex":[0.9998376,0.00001177265,0.00001396994,0.00005864762,0.00005609082,0.000021823],"domain_scores_gemma":[0.9998411,0.00004286071,0.00002885639,0.00002500458,0.00003813911,0.00002398991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000852673,0.000003066703,0.0002806749,0.00001207211,0.000002028543,0.00003378723,0.00001851204,0.00001641918,0.9987692,0.00003404676,0.00001123402,0.0008103786],"study_design_scores_gemma":[0.000003096168,0.00007341131,0.03037495,0.00001093637,0.00002487031,0.0005006109,0.0001297632,0.00124326,0.9622883,0.0002157647,0.005126245,0.000008660279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8575138,0.003072249,0.1256192,0.0001274125,0.000119297,0.0001448521,0.004527817,0.000566992,0.008308328],"genre_scores_gemma":[0.9277716,0.001939208,0.05758194,0.0002351529,0.00003347512,0.0002916291,0.005506823,0.0003145382,0.006325633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001269014,"threshold_uncertainty_score":0.004245281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02639025327095496,"score_gpt":0.3127977953876713,"score_spread":0.2864075421167163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}