{"id":"W4220663453","doi":"10.1038/s41429-022-00517-7","title":"Halovirs I–K, antibacterial and cytotoxic lipopeptaibols from the plant pathogenic fungus Paramyrothecium roridum NRRL 2183","year":2022,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Biotechnology Research Institute","funders":"National Natural Science Foundation of China","keywords":"HeLa; Fungus; Mycelium; Stereochemistry; Pathogenic fungus; Antibacterial activity; Cytotoxicity; Biology; Amino acid; Gene; Antibiotics; Two-dimensional nuclear magnetic resonance spectroscopy; Microbiology; Chemistry; Bacteria; Biochemistry; In vitro; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105942,0.0004007683,0.0002295308,0.0002425328,0.0001651871,0.0002737326,0.0001951392,0.0002059426,0.0009074312],"category_scores_gemma":[0.0002329874,0.0001570352,0.0002466901,0.0002257073,0.0002277445,0.0002076198,0.0002857175,0.000445082,0.0003761304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001912857,"about_ca_system_score_gemma":0.0002362739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005486173,"about_ca_topic_score_gemma":0.0004872109,"domain_scores_codex":[0.9998786,0.00002157289,0.00001358627,0.0000149257,0.0000379231,0.00003331506],"domain_scores_gemma":[0.9998924,0.00002434098,0.00002047678,0.00001232654,0.00001865131,0.00003183036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000324692,0.0000107202,0.0002294531,0.00003858919,0.000005815699,0.0001328824,0.00001902498,0.00008143391,0.9972689,0.0000500263,0.00003963022,0.001798858],"study_design_scores_gemma":[0.00005569445,0.0004938405,0.007017975,0.00001229162,0.0000251201,0.0006101659,0.00009232751,0.0003299942,0.9879392,0.00009881859,0.003314211,0.00001031647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927771,0.002076094,0.001913788,0.00009539815,0.00002826361,0.00005789613,0.0007571832,0.00004733372,0.002246908],"genre_scores_gemma":[0.9931865,0.001290651,0.001268718,0.00006444581,0.00001449522,0.00002722844,0.002241725,0.00002740961,0.001878899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009074312,"threshold_uncertainty_score":0.003035605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839210548184024,"score_gpt":0.2229865616057262,"score_spread":0.2045944561238859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}