{"id":"W4220663751","doi":"10.1007/s40261-022-01129-7","title":"Multiple Sclerosis Relapses Following Cessation of Fingolimod","year":2022,"lang":"en","type":"article","venue":"Clinical Drug Investigation","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre intégré de santé et de services sociaux de Chaudière-Appalaches","funders":"National Health and Medical Research Council; Grifols; Multiple Sclerosis Society; Multiple Sclerosis International Federation; Acorda Therapeutics; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Teva Pharmaceutical Industries; Biogen; Celgene; Fondazione Italiana Sclerosi Multipla; Sanofi Genzyme; University of Melbourne; Sanofi","keywords":"Fingolimod; Medicine; Smoking cessation; Multiple sclerosis; Internal medicine; Pharmacotherapy; Disease; Physical therapy; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001782358,0.0001676475,0.0006414232,0.0008004935,0.0002705104,0.0006818469,0.0003612255,0.0003238669,0.002524908],"category_scores_gemma":[0.008216972,0.0001506534,0.0008050231,0.0009927928,0.000192947,0.0003771828,0.0004519724,0.0007147224,0.0004109761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004740545,"about_ca_system_score_gemma":0.0003303637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002174153,"about_ca_topic_score_gemma":0.002218656,"domain_scores_codex":[0.9980403,0.0004170371,0.0003093608,0.0003406426,0.0006713205,0.0002213632],"domain_scores_gemma":[0.9906109,0.001899867,0.006449785,0.000359301,0.0003948903,0.0002851861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005747625,0.00005000058,0.9808761,0.0001726608,0.0002762452,0.0004321114,0.0001382865,0.0001333973,0.0002721321,0.00004195064,0.0008614993,0.01617076],"study_design_scores_gemma":[0.00001396593,0.00009493327,0.9974555,0.00007563812,0.00007975633,0.001328546,0.00005924817,0.0001587962,0.0001314643,0.00005296127,0.0005437144,0.000005436303],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925598,0.003334669,0.0001941709,0.0002743683,0.00002025081,0.000034513,0.001564881,0.00003483109,0.001982516],"genre_scores_gemma":[0.9975587,0.0008786267,0.00008522006,0.0000881384,0.00005000807,0.00001578234,0.00112336,0.000005682603,0.0001944097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002524908,"threshold_uncertainty_score":0.009426117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1972093104389497,"score_gpt":0.3747379330857507,"score_spread":0.177528622646801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}