{"id":"W4220673029","doi":"10.1158/1538-7445.sabcs21-pd14-08","title":"Abstract PD14-08: Effectiveness of aromatase inhibitors versus tamoxifen in lobular compared to ductal carcinoma: Individual patient data meta-analysis of 9328 women with central histopathology, and 7654 women with e-Cadherin status","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Tamoxifen; Medicine; Breast cancer; Lobular carcinoma; Ductal carcinoma; Invasive lobular carcinoma; Oncology; Internal medicine; Aromatase; Cancer; Selective estrogen receptor modulator; Gynecology; Pathology; Invasive ductal carcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02256634,0.003176715,0.01592949,0.002190226,0.000488146,0.003454779,0.002188394,0.002647622,0.003979946],"category_scores_gemma":[0.02815751,0.001454469,0.05437428,0.002973611,0.0008672291,0.001758728,0.001696968,0.003530521,0.0005378613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001456446,"about_ca_system_score_gemma":0.001053781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004144004,"about_ca_topic_score_gemma":0.005400416,"domain_scores_codex":[0.9807575,0.01399767,0.001990979,0.001937609,0.0009483338,0.0003680473],"domain_scores_gemma":[0.9834307,0.01199083,0.002259309,0.00112974,0.0007829055,0.0004064677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0255236,0.00003366467,0.004279466,0.01533007,0.9506208,0.0000801534,0.00002883842,0.0009911964,0.0003758571,0.00007846925,0.0004682751,0.00218957],"study_design_scores_gemma":[0.006749982,0.0007080922,0.003911627,0.0006189774,0.9862324,0.00006426802,0.00002734299,0.000563785,0.0001592151,0.0002255289,0.000715778,0.00002294991],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2268396,0.7477255,0.008470209,0.00156759,0.001926948,0.001584891,0.008446139,0.0004787928,0.002960357],"genre_scores_gemma":[0.9588363,0.03096914,0.003032282,0.001549645,0.0003368157,0.001273703,0.002612683,0.0001252255,0.001264248],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02256634,"threshold_uncertainty_score":0.1193436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06216226501604589,"score_gpt":0.3350366736392085,"score_spread":0.2728744086231626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}