{"id":"W4220696785","doi":"10.3390/microorganisms10040742","title":"Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by Cariogenic S. mutans Biofilm","year":2022,"lang":"en","type":"article","venue":"Microorganisms","topic":"Dental Erosion and Treatment","field":"Dentistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canada Foundation for Innovation","keywords":"Demineralization; Biofilm; Enamel paint; Streptococcus mutans; Dentistry; Saliva; Microbiology; Chemistry; Biology; Medicine; Biochemistry; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001146498,0.0002570588,0.0002299573,0.0001011926,0.0003593078,0.00008267722,0.0003098212,0.00008211836,0.003690613],"category_scores_gemma":[0.0000191301,0.0002670931,0.0001271021,0.0003945213,0.00005299768,0.00009593097,0.0002315534,0.0002045056,0.0005796098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003903302,"about_ca_system_score_gemma":0.00006586135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002854193,"about_ca_topic_score_gemma":0.0000331321,"domain_scores_codex":[0.9984086,0.00009885861,0.0003347326,0.0004509264,0.0003617682,0.0003451751],"domain_scores_gemma":[0.9993234,0.0000224572,0.0001104661,0.0003828463,0.00003728774,0.0001235906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002942784,0.0003010941,0.001250018,0.00001306699,0.00006713688,0.000113166,0.0003798277,0.00003955538,0.9145421,0.0001747661,0.08270539,0.0003844976],"study_design_scores_gemma":[0.001672544,0.0001737341,0.003038973,0.00001022583,0.0001050331,0.0005760944,0.0006536692,0.00008884617,0.9606979,0.0001359534,0.03241792,0.0004290354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994784,0.0009575436,0.0003524152,0.0002552745,0.001000502,0.0004724652,0.0006533408,0.000323635,0.001200824],"genre_scores_gemma":[0.9701644,0.00001763942,0.0005705059,0.0004152754,0.00005453157,0.0001068041,0.001409987,0.00008169105,0.02717918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05028747,"threshold_uncertainty_score":0.9999781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008605437141212395,"score_gpt":0.2269239882699491,"score_spread":0.2183185511287367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}