{"id":"W4220696785","doi":"10.3390/microorganisms10040742","title":"Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by Cariogenic S. mutans Biofilm","year":2022,"lang":"en","type":"article","venue":"Microorganisms","topic":"Dental Erosion and Treatment","field":"Dentistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canada Foundation for Innovation","keywords":"Demineralization; Biofilm; Enamel paint; Streptococcus mutans; Dentistry; Saliva; Microbiology; Chemistry; Biology; Medicine; Biochemistry; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001939883,0.0003543419,0.0002566162,0.000110491,0.00007251602,0.0002159813,0.0001458445,0.0002694039,0.0007259491],"category_scores_gemma":[0.0001494216,0.0001129251,0.0002070771,0.00006731816,0.0001288026,0.0001681492,0.0002157628,0.0003409724,0.0001071845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008529264,"about_ca_system_score_gemma":0.000136462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001889049,"about_ca_topic_score_gemma":0.0002945881,"domain_scores_codex":[0.9998507,0.00003088732,0.00001868702,0.00002590373,0.00004768612,0.00002608774],"domain_scores_gemma":[0.9999141,0.00001668129,0.00003038049,0.000006367812,0.00001529518,0.00001721679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007115058,0.00003551856,0.00006055189,0.00003151993,0.000003695415,0.00001080876,0.000005353308,0.00002180995,0.9989064,0.000008026563,0.000005907003,0.0008392819],"study_design_scores_gemma":[0.0000176167,0.0009361235,0.00319216,0.000005655319,0.00002296846,0.00009272467,0.00002797607,0.0003541858,0.9945878,0.00001129886,0.00074789,0.00000357395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985367,0.0006593007,0.0005296202,0.000018042,0.000009214871,0.00001442009,0.00003543009,0.000009000551,0.0001882659],"genre_scores_gemma":[0.9962249,0.0006432174,0.002293559,0.00003150176,0.000006580082,0.00002151407,0.000112819,0.000006102935,0.000659814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007259491,"threshold_uncertainty_score":0.002428532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008605437141212395,"score_gpt":0.2269239882699491,"score_spread":0.2183185511287367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}