{"id":"W4220704062","doi":"10.1016/j.immuni.2022.02.003","title":"A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts","year":2022,"lang":"en","type":"article","venue":"Immunity","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Biology; Interleukin 22; Citrobacter rodentium; Chemokine; Proinflammatory cytokine; Immunology; Innate immune system; T cell; Innate lymphoid cell; Immune system; Microbiology; Interleukin; CXCL1; Interleukin 17; Cell biology; Cytokine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005069249,0.0001614321,0.0003710838,0.0001357122,0.0003357761,0.000008154097,0.0003901997,0.0001312594,0.0005390929],"category_scores_gemma":[0.000109783,0.0001708825,0.0001274254,0.0001739707,0.0001625002,0.00006068232,0.0003398471,0.0004585188,0.0000366073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009902693,"about_ca_system_score_gemma":0.0002310935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001193443,"about_ca_topic_score_gemma":0.0002628669,"domain_scores_codex":[0.9984156,0.0005816923,0.0003858321,0.0002051614,0.00003413316,0.0003776115],"domain_scores_gemma":[0.9991688,0.0002007619,0.0001845089,0.0003614928,0.00006947965,0.00001495742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001851171,0.0006582089,0.0005764784,0.00004210792,0.00005320271,0.000004582671,0.004874544,0.000009568151,0.9904936,0.0001784979,0.0008144219,0.0004436162],"study_design_scores_gemma":[0.006885177,0.001948728,0.01097986,0.00003105485,0.00004497989,0.00004524526,0.004793722,0.00001486079,0.8506243,0.0003817073,0.1239162,0.0003341394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944398,0.0004799772,0.00005212055,0.00002188365,0.00126583,0.0004499152,0.00238965,0.00003366945,0.0008671807],"genre_scores_gemma":[0.9987168,0.00003022827,0.00008297949,0.00006162033,0.00002061351,0.0001041698,0.0004775334,0.00002004744,0.0004859893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1398693,"threshold_uncertainty_score":0.6968384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01332712548087685,"score_gpt":0.232234181961389,"score_spread":0.2189070564805121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}