{"id":"W4220704062","doi":"10.1016/j.immuni.2022.02.003","title":"A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts","year":2022,"lang":"en","type":"article","venue":"Immunity","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Biology; Interleukin 22; Citrobacter rodentium; Chemokine; Proinflammatory cytokine; Immunology; Innate immune system; T cell; Innate lymphoid cell; Immune system; Microbiology; Interleukin; CXCL1; Interleukin 17; Cell biology; Cytokine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755128,0.0004973218,0.0002846604,0.0003299482,0.0003628278,0.0005911886,0.0001620758,0.0002924323,0.001166834],"category_scores_gemma":[0.0001662785,0.0001234143,0.0002078167,0.0001275809,0.0003877899,0.0003628821,0.0004511558,0.0006168137,0.000176502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002926072,"about_ca_system_score_gemma":0.0006070672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006117798,"about_ca_topic_score_gemma":0.001400084,"domain_scores_codex":[0.9997889,0.00004440807,0.0000110517,0.00002766885,0.00003722235,0.00009067249],"domain_scores_gemma":[0.9998211,0.00001239701,0.00002831799,0.000016058,0.00003092071,0.00009124506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006621826,0.00004204733,0.001680876,0.000121793,0.00001260518,0.0007061735,0.00004669785,0.0001444862,0.9901242,0.0008035493,0.0002113921,0.005444088],"study_design_scores_gemma":[0.0004070704,0.002829148,0.1819388,0.0002213077,0.0001862917,0.004720378,0.001600302,0.009167576,0.7767492,0.003338519,0.01878237,0.00005902887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803753,0.01256358,0.003073387,0.0007507158,0.00007514389,0.00002906292,0.0001804855,0.00006405851,0.0028882],"genre_scores_gemma":[0.9955214,0.00178838,0.001151625,0.00008492752,0.00003427506,0.00001664486,0.00009465437,0.00000511988,0.001302799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001166834,"threshold_uncertainty_score":0.003903389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01332712548087685,"score_gpt":0.232234181961389,"score_spread":0.2189070564805121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}