{"id":"W4220704970","doi":"10.3390/microorganisms10040708","title":"The Tip of Brucella O-Polysaccharide Is a Potent Epitope in Response to Brucellosis Infection and Enables Short Synthetic Antigens to Be Superior Diagnostic Reagents","year":2022,"lang":"en","type":"article","venue":"Microorganisms","topic":"Brucella: diagnosis, epidemiology, treatment","field":"Veterinary","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Animal and Plant Health Agency","keywords":"Brucellosis; Brucella; Epitope; Brucella abortus; Antigen; Brucellaceae; Microbiology; Virology; Polysaccharide; Biology; Chemistry; Immunology; Brucella melitensis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00205949,0.0004078441,0.000628464,0.0003795574,0.0005634471,0.00006025734,0.0004306229,0.0001384034,0.0003789691],"category_scores_gemma":[0.001531573,0.0003660431,0.0001523825,0.0006449569,0.0001387429,0.00005927066,0.000917081,0.0003085556,0.0001102343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005654074,"about_ca_system_score_gemma":0.0001050723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003558416,"about_ca_topic_score_gemma":0.0006006748,"domain_scores_codex":[0.9958652,0.001327395,0.0008736307,0.0008783987,0.0003305589,0.0007248057],"domain_scores_gemma":[0.9957565,0.002905615,0.0001367473,0.0008719569,0.00007277002,0.0002563937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001267345,0.0004643863,0.09673048,0.00003339814,0.0001176638,0.0003005377,0.004701872,0.000110073,0.8873569,0.00001679495,0.004542741,0.004357858],"study_design_scores_gemma":[0.000870064,0.003544477,0.4434652,0.0001198723,0.0001830132,0.0006392411,0.001564289,0.0000320502,0.5230065,0.0001391612,0.02574392,0.0006922162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877877,0.001231068,0.00003798482,0.008650496,0.0004461133,0.001526897,0.0002226875,0.00006738752,0.00002972143],"genre_scores_gemma":[0.995028,0.001030854,0.0005571824,0.002426236,0.00003876036,0.0005648158,0.00001012249,0.00009421796,0.0002498544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3643503,"threshold_uncertainty_score":0.9998792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04292009852503402,"score_gpt":0.3051641656132719,"score_spread":0.2622440670882379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}