{"id":"W4220717457","doi":"10.1093/jnci/djac053","title":"CD4/CD8 Ratio and Cancer Risk Among Adults With HIV","year":2022,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institute on Aging; National Eye Institute; National Heart, Lung, and Blood Institute; National Institute of Mental Health; Eli Lilly and Company; National Institute on Drug Abuse; National Institute on Minority Health and Health Disparities; National Center for Research Resources; Centers for Disease Control and Prevention; National Institute on Alcohol Abuse and Alcoholism; National Cancer Institute; National Institutes of Health; Gilead Sciences","keywords":"Medicine; Hazard ratio; Internal medicine; Interquartile range; Cancer; Lung cancer; CD4-CD8 Ratio; Confidence interval; Oncology; Cohort; Colorectal cancer; Cohort study; Sarcoma; Immunology; CD8; Immune system; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755196,0.0001335211,0.0001186255,0.000299819,0.000292108,0.0004209775,0.0002757709,0.0002016078,0.001440642],"category_scores_gemma":[0.001469509,0.0001322426,0.0001892626,0.0004771993,0.0001400538,0.0002704232,0.0002406089,0.0005111397,0.00009696235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004333352,"about_ca_system_score_gemma":0.0005052952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03350092,"about_ca_topic_score_gemma":0.02932011,"domain_scores_codex":[0.9998691,0.00002046586,0.00001012509,0.00003353002,0.00002927037,0.00003743695],"domain_scores_gemma":[0.9995047,0.00008711351,0.0002329307,0.00002526179,0.00007284412,0.00007714798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004988134,0.00001137994,0.9984156,0.000006505539,0.00002247299,0.00001983537,0.0000157117,0.0000588567,0.00003879254,0.00002440714,0.0001066069,0.001229838],"study_design_scores_gemma":[0.000008370821,0.00005686548,0.9981024,0.00001468866,0.00004520009,0.0002126273,0.0001108266,0.0008672435,0.00008642345,0.00008182049,0.0004105499,0.000003051956],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977301,0.0009054326,0.00009395178,0.0001018583,0.000008700815,0.000007153827,0.0006296671,0.000007339122,0.0005158913],"genre_scores_gemma":[0.999392,0.0001419994,0.00006380668,0.00001993849,0.000005923592,0.000003028287,0.000248369,0.000001047359,0.0001239202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03350092,"threshold_uncertainty_score":0.06661183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562788008252426,"score_gpt":0.2810871766228259,"score_spread":0.2654592965403016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}