{"id":"W4220726792","doi":"10.1371/journal.ppat.1010337","title":"HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Australian Synchrotron; Monash Biomedicine Discovery Institute, Monash University; National Health and Medical Research Council; Australian Research Council; Australian Nuclear Science and Technology Organisation; Medical Research Council; University of Melbourne; Monash University; Australian Institute of Nuclear Science and Engineering; Australian Cancer Research Foundation; Australian Government","keywords":"Epitope; Immunogenicity; Virology; Biology; Human leukocyte antigen; Immunity; CD8; Antigen; Influenza A virus; Influenza vaccine; Immunology; Immune system; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002356157,0.000308162,0.0003400706,0.000187252,0.0005294026,0.00007621874,0.0003032136,0.0001573966,0.00001228483],"category_scores_gemma":[0.00005340194,0.0003193806,0.00007033969,0.0003358507,0.00004714566,0.00001860488,0.0007709442,0.0003177982,0.000004158173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004724246,"about_ca_system_score_gemma":0.0001732819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003631091,"about_ca_topic_score_gemma":0.000264195,"domain_scores_codex":[0.9983178,0.0001170214,0.0004927724,0.0003624266,0.0002043642,0.0005056513],"domain_scores_gemma":[0.9990696,0.00002998207,0.0002063616,0.0005147755,0.00005438558,0.0001248567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000150049,0.0004741166,0.3376075,0.000145701,0.00007689989,0.00001844972,0.01189641,0.0004728456,0.6481245,0.00000227813,0.00003763916,0.0009935695],"study_design_scores_gemma":[0.008477881,0.002747144,0.8007898,0.0000665001,0.0002409849,0.0001806791,0.01647182,0.00233375,0.141281,0.0000627296,0.02496632,0.00238138],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965424,0.002273795,0.00001353266,0.000009330592,0.00004691768,0.0006526245,0.0002247627,0.00002298514,0.0002136817],"genre_scores_gemma":[0.9977186,0.0004155622,0.0002873665,0.001155907,0.00004030275,0.0001533579,0.0001577893,0.00004752354,0.0000235575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5068436,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785688067192667,"score_gpt":0.2346220730985057,"score_spread":0.216765192426579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}