{"id":"W4220726792","doi":"10.1371/journal.ppat.1010337","title":"HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Australian Synchrotron; Monash Biomedicine Discovery Institute, Monash University; National Health and Medical Research Council; Australian Research Council; Australian Nuclear Science and Technology Organisation; Medical Research Council; University of Melbourne; Monash University; Australian Institute of Nuclear Science and Engineering; Australian Cancer Research Foundation; Australian Government","keywords":"Epitope; Immunogenicity; Virology; Biology; Human leukocyte antigen; Immunity; CD8; Antigen; Influenza A virus; Influenza vaccine; Immunology; Immune system; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001507683,0.000115902,0.0001245839,0.00009910112,0.0002002629,0.0001881112,0.00009534497,0.0001983744,0.001298145],"category_scores_gemma":[0.0002264385,0.0001200466,0.0001285656,0.00007844919,0.0001776225,0.0001414559,0.0002070094,0.0002337905,0.0002450943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001210391,"about_ca_system_score_gemma":0.0001381127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002846679,"about_ca_topic_score_gemma":0.003126083,"domain_scores_codex":[0.9999291,0.000009569341,0.000005461507,0.00002183357,0.00001487204,0.00001916097],"domain_scores_gemma":[0.9999388,0.000008153867,0.00001043108,0.000006142359,0.0000165337,0.00001984182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006456914,0.0002145356,0.1838011,0.0002155497,0.0000490777,0.0008714398,0.00288277,0.000207803,0.7917491,0.0001891074,0.0002551744,0.01891864],"study_design_scores_gemma":[0.00002334869,0.001199474,0.9757883,0.00002183482,0.00004613875,0.00154726,0.001633948,0.0005427498,0.01712984,0.0001241313,0.001932964,0.00001004376],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993649,0.00008787812,0.00006225432,0.00001347269,0.000001835856,0.000006678784,0.00002490264,0.000001004615,0.0004370627],"genre_scores_gemma":[0.9984842,0.0001284262,0.000163337,0.00004826424,0.000004090322,0.00001018098,0.00007211067,7.937494e-7,0.001088648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002846679,"threshold_uncertainty_score":0.005660176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785688067192667,"score_gpt":0.2346220730985057,"score_spread":0.216765192426579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}