{"id":"W4220734028","doi":"10.1158/1538-7445.sabcs21-p1-18-25","title":"Abstract P1-18-25: Real-world quality of life (QoL) in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), advanced breast cancer (ABC) treated with palbociclib: A patient-reported outcome (PRO) analysis from POLARIS","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Palbociclib; Medicine; Cancer; Internal medicine; Oncology; Quality of life (healthcare); Breast cancer; Metastatic breast cancer; Stage (stratigraphy); Disease; Cohort; Gynecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008569171,0.0007673497,0.002219711,0.001785928,0.0006172447,0.00005009765,0.000522652,0.0001786132,0.007330299],"category_scores_gemma":[0.0002438295,0.0006276986,0.0003198264,0.007244298,0.0008925187,0.0005879827,0.0003116114,0.002054549,0.00000647195],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00441703,"about_ca_system_score_gemma":0.001243515,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.2024641,"about_ca_topic_score_gemma":0.01856743,"domain_scores_codex":[0.9906021,0.001183522,0.001871083,0.001684002,0.003271423,0.001387837],"domain_scores_gemma":[0.9935759,0.0007411924,0.001489921,0.001136762,0.002356495,0.0006997338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03922859,0.001382385,0.9304577,0.000129838,0.00432208,0.00004100278,0.003313144,0.0003870534,0.01301915,0.00001592625,0.0001135288,0.007589565],"study_design_scores_gemma":[0.01379632,0.001591477,0.9753084,0.0002689533,0.0003777777,0.000001052239,0.002467816,0.000009699407,0.005338728,0.00002503911,0.0001163973,0.00069835],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856035,0.0006333197,0.00001752458,0.0008123421,0.00007794481,0.002866984,0.009542668,0.0001291022,0.0003166411],"genre_scores_gemma":[0.9952106,0.0001760692,0.0004679916,0.0001733592,0.0001257643,0.002051045,0.001227026,0.0002013119,0.0003668469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1838967,"threshold_uncertainty_score":0.9996175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06712141622283398,"score_gpt":0.3906830873880279,"score_spread":0.323561671165194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}