{"id":"W4220734220","doi":"10.1128/spectrum.02593-21","title":"Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Tracheal and airway disorders","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"National Key Research and Development Program of China; Medical Science and Technology Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Endotype; Resistome; Pulmonary disease; Airway; Medicine; COPD; Disease; Immunology; Antibiotics; Biology; Microbiology; Internal medicine; Antibiotic resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001644454,0.0001937467,0.0003257182,0.0002361765,0.0001853246,0.000003803431,0.0001594867,0.00008881916,0.00123153],"category_scores_gemma":[0.0000390107,0.0001954177,0.0001286831,0.0003322957,0.0001854837,0.00003901113,0.0001566541,0.0006294823,0.00008862152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001232352,"about_ca_system_score_gemma":0.0004353847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000103675,"about_ca_topic_score_gemma":0.0003564464,"domain_scores_codex":[0.9984987,0.0001798925,0.0002925287,0.0004273789,0.00007505856,0.000526395],"domain_scores_gemma":[0.9994587,0.00004874594,0.00009648871,0.0002590024,0.00001400579,0.0001230113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002491852,0.001219664,0.4727518,0.0001358693,0.0002047168,0.00229756,0.0004862557,0.000447295,0.5131952,0.001220163,0.002984912,0.002564686],"study_design_scores_gemma":[0.002330409,0.0004460834,0.9612919,0.00003039067,0.00006567104,0.000152546,0.0002938445,0.00007887575,0.001833624,0.0009149611,0.03222449,0.0003371946],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904197,0.002773418,0.000001139763,0.003781152,0.000279849,0.0004147732,0.0001591453,0.0001207692,0.002050031],"genre_scores_gemma":[0.9961407,0.00003920523,0.00001069314,0.0004761088,0.00007608251,0.00009212572,0.0004357724,0.00002956533,0.002699762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5113616,"threshold_uncertainty_score":0.9996815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00603254520508278,"score_gpt":0.215001003047882,"score_spread":0.2089684578427992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}