{"id":"W4220743135","doi":"10.1021/acssynbio.1c00524","title":"Conjugation-Based Genome Engineering in <i>Deinococcus radiodurans</i>","year":2022,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deinococcus radiodurans; Plasmid; Genome; Genome engineering; Biology; Synthetic biology; Computational biology; Genetics; Genome editing; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023787,0.0001700492,0.0001981077,0.0001294841,0.0000865808,0.000008548004,0.000359435,0.0002231634,0.0001189635],"category_scores_gemma":[0.00005674857,0.0001789442,0.00006327921,0.0001780931,0.0001060052,0.000001034897,0.000194179,0.0002047018,0.000008331717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003662041,"about_ca_system_score_gemma":0.00007774002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002922994,"about_ca_topic_score_gemma":0.00001544695,"domain_scores_codex":[0.9987819,0.0001066518,0.0002573676,0.0004379764,0.00005746968,0.0003585891],"domain_scores_gemma":[0.9994459,0.00002512025,0.00006738661,0.000393109,0.00002338219,0.00004510039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005856015,0.00006109181,0.001505753,0.000006498341,0.00001756047,0.000004734647,0.00001325736,0.00178396,0.9948375,0.0004189477,0.00004214071,0.001250048],"study_design_scores_gemma":[0.001849539,0.001303095,0.003843777,0.000005514933,0.00001926027,0.00007256676,0.00004041894,0.0006713811,0.6415085,0.00021021,0.3499114,0.0005643409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970648,0.0006961465,0.0005723824,0.000827974,0.0003242479,0.0002340142,0.00007012004,0.00002979221,0.0001805558],"genre_scores_gemma":[0.9984875,0.00006515071,0.0003614734,0.0004942823,0.00009496647,0.0001427053,0.000273911,0.00002545724,0.00005457729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.353329,"threshold_uncertainty_score":0.7297134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005165109368468879,"score_gpt":0.1974856478091934,"score_spread":0.1923205384407246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}