{"id":"W4220743135","doi":"10.1021/acssynbio.1c00524","title":"Conjugation-Based Genome Engineering in <i>Deinococcus radiodurans</i>","year":2022,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deinococcus radiodurans; Plasmid; Genome; Genome engineering; Biology; Synthetic biology; Computational biology; Genetics; Genome editing; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003069762,0.0005529504,0.0002492743,0.0002596415,0.0002009174,0.0003543065,0.0004601786,0.0003872738,0.001162731],"category_scores_gemma":[0.0003756409,0.0002421479,0.0004036856,0.0003212362,0.0002759363,0.000265718,0.000572671,0.0008631874,0.001063041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000350127,"about_ca_system_score_gemma":0.0002650046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000912136,"about_ca_topic_score_gemma":0.001061524,"domain_scores_codex":[0.999656,0.0001008382,0.00004352898,0.00005719032,0.00008962523,0.00005284783],"domain_scores_gemma":[0.9998129,0.0000385749,0.00006097684,0.00004429941,0.00001938643,0.0000238139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003756479,0.00002810311,0.00008615937,0.00003019277,0.0000052958,0.00003630212,0.00001680453,0.00007357923,0.9977103,0.0003476255,0.0000849964,0.001543025],"study_design_scores_gemma":[0.000008482447,0.0001002366,0.0006110671,0.000003637204,0.00001164397,0.0002107903,0.00001301975,0.0004261089,0.9952255,0.00005784209,0.003325457,0.00000629423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9100155,0.001432046,0.07545656,0.0005610352,0.0002379512,0.0005519393,0.002240526,0.001238281,0.008266175],"genre_scores_gemma":[0.9452951,0.0009585813,0.04218959,0.0001270998,0.00001918089,0.0001995978,0.002935543,0.0003899662,0.007885508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162731,"threshold_uncertainty_score":0.00388974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005165109368468879,"score_gpt":0.1974856478091934,"score_spread":0.1923205384407246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}