{"id":"W4220752201","doi":"10.21203/rs.3.rs-1451790/v1","title":"The Biota Orientalis Oil Extract, Epiitalis®, Is Efficacious At Reducing The Symptoms Of Knee Osteoarthritis: A Pilot, Multi-Site, Dose-Ranging, Randomized, Blinded, Placebo-Controlled Trial","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eli Lilly and Company","keywords":"Osteoarthritis; Dose-ranging study; Randomized controlled trial; Medicine; Placebo; Double blinded; Physical therapy; Internal medicine; Alternative medicine; Pathology; Double blind","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001111163,0.0008968069,0.00168703,0.000273319,0.0002898653,0.0005828108,0.0005322161,0.0008717605,0.004757249],"category_scores_gemma":[0.0008647664,0.0003806507,0.0009889421,0.0003018162,0.0005675296,0.0004217218,0.0002006228,0.001190778,0.0005348687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002460388,"about_ca_system_score_gemma":0.0005153219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004372686,"about_ca_topic_score_gemma":0.001061119,"domain_scores_codex":[0.9996208,0.0002079537,0.00004000368,0.00005638164,0.00003865645,0.00003615365],"domain_scores_gemma":[0.9994321,0.0001714631,0.0001499304,0.00004211521,0.00006053184,0.0001438746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.959135,0.01048618,0.0005516146,0.001091552,0.0009477125,0.00003727916,0.00004287136,0.0001027664,0.009365235,0.00003845772,0.000279425,0.01792201],"study_design_scores_gemma":[0.7685493,0.2243274,0.004050891,0.00005122483,0.0008292937,0.00003933163,0.00003004196,0.0002231225,0.001296152,0.00003277317,0.0005584874,0.00001190286],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897696,0.005134281,0.0004305235,0.0002279499,0.0002382458,0.002367142,0.0005148328,0.00006906378,0.001248486],"genre_scores_gemma":[0.9920549,0.002788684,0.0008163607,0.0003575631,0.0003377536,0.001629692,0.0003802922,0.000008499493,0.001626233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004757249,"threshold_uncertainty_score":0.01591462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04504548924296201,"score_gpt":0.3588221000624157,"score_spread":0.3137766108194536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}