{"id":"W4220761486","doi":"10.1016/j.msard.2022.103779","title":"Mesenchymal stem cell therapy and cognition in MS: Preliminary findings from a phase II clinical trial","year":2022,"lang":"en","type":"article","venue":"Multiple Sclerosis and Related Disorders","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; University of Manitoba; Ottawa Hospital; University of Ottawa","funders":"Multiple Sclerosis Society of Canada","keywords":"Mesenchymal stem cell; Medicine; Multiple sclerosis; Clinical trial; Cognition; Stem-cell therapy; Cell therapy; Stem cell; Oncology; Internal medicine; Pathology; Immunology; Psychiatry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001023711,0.000219769,0.0004733715,0.0002147186,0.0004743444,0.00003265728,0.0001033663,0.0002285601,0.0008116922],"category_scores_gemma":[0.00009905337,0.0001915007,0.0001404896,0.0003522744,0.0002137897,0.00009650241,0.0002686172,0.0009174558,0.000007436094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004907404,"about_ca_system_score_gemma":0.00008150716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004225913,"about_ca_topic_score_gemma":0.00003505843,"domain_scores_codex":[0.9973333,0.0004563177,0.0006886965,0.0006456933,0.0004898809,0.0003861364],"domain_scores_gemma":[0.9987417,0.0006359486,0.0001190816,0.0002231055,0.00003104301,0.0002491591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2513166,0.01719072,0.1324779,0.0001298029,0.0004821276,0.0001269828,0.009510589,0.00005650756,0.03206874,0.00001955091,0.00212046,0.5545],"study_design_scores_gemma":[0.7027232,0.03366952,0.2256847,0.0002813282,0.0002123384,0.00001784172,0.007011968,0.02191494,0.001094196,0.0002326746,0.006464759,0.0006925268],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990636,0.005143183,0.000004204075,0.0008603458,0.0002773362,0.002029096,0.00006120925,0.00004844523,0.0009402191],"genre_scores_gemma":[0.9909092,0.007885331,0.0000606279,0.0001218962,0.00004271307,0.0002125947,0.000167849,0.00003687614,0.0005628737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5538074,"threshold_uncertainty_score":0.888746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1066146419889372,"score_gpt":0.3299668980979571,"score_spread":0.2233522561090198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}