{"id":"W4220777540","doi":"10.1186/s40001-022-00638-7","title":"Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer","year":2022,"lang":"en","type":"article","venue":"European journal of medical research","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Princess Margaret Cancer Centre; Sinai Health System; Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto","funders":"National Cancer Institute; National Institutes of Health; Division of Cancer Epidemiology and Genetics, National Cancer Institute; Georg-August-Universität Göttingen; World Health Organization","keywords":"AXIN2; Lung cancer; Wnt signaling pathway; Carcinogenesis; Biology; Cancer; Odds ratio; Single-nucleotide polymorphism; Oncology; Cancer research; Bioinformatics; Internal medicine; Medicine; Genetics; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004010276,0.0002741202,0.0003085004,0.0004686168,0.0001450205,0.0002777117,0.0001701209,0.0003023227,0.003535073],"category_scores_gemma":[0.0008883279,0.00009755796,0.0006815828,0.0004933155,0.0002557222,0.00009161841,0.0002144203,0.0002724415,0.0002047094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001807778,"about_ca_system_score_gemma":0.0001555013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00166863,"about_ca_topic_score_gemma":0.001762113,"domain_scores_codex":[0.9995489,0.000146584,0.00003677268,0.0001540676,0.0000591833,0.00005448369],"domain_scores_gemma":[0.9993131,0.0003489818,0.0001699117,0.0000590838,0.00002583914,0.00008310185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005891435,0.0001418062,0.7430252,0.0001136211,0.001455373,0.0009476647,0.0001099851,0.001748622,0.2334293,0.0004034277,0.0002715159,0.01246208],"study_design_scores_gemma":[0.00004396122,0.0002377854,0.9836022,0.000007652556,0.0004867974,0.0008239605,0.00004807996,0.004337135,0.009627495,0.000296842,0.0004773859,0.00001082502],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981518,0.0002421225,0.0009563576,0.00003565743,0.000006055975,0.000004789601,0.0003504497,0.00001880796,0.0002338639],"genre_scores_gemma":[0.9992124,0.0000422228,0.0004118462,0.000009571733,0.000002885936,0.000004640752,0.000145907,0.000005909393,0.0001646826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003535073,"threshold_uncertainty_score":0.01182598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04323006407259349,"score_gpt":0.378275576605181,"score_spread":0.3350455125325875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}