{"id":"W4220778580","doi":"10.1038/s41398-022-01902-4","title":"DNA methylation signatures in human neonatal blood following maternal antenatal corticosteroid treatment","year":2022,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"University of Toronto; Government of Canada; CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Government of Ontario","keywords":"DNA methylation; Epigenetics; Methylation; CpG site; Medicine; Gene; Epigenome; Biology; Bioinformatics; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646688,0.0001592802,0.0001258911,0.0001093376,0.0002153986,0.00002125848,0.0001218392,0.00007773229,0.0001201088],"category_scores_gemma":[0.000003579855,0.000169148,0.0001553898,0.0001173846,0.00001874049,0.000008663114,0.0000272686,0.000116085,0.000001424528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002214982,"about_ca_system_score_gemma":0.00008563399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004298053,"about_ca_topic_score_gemma":0.0002278284,"domain_scores_codex":[0.9987849,0.00009913544,0.0003091144,0.0003363036,0.0002763325,0.0001942262],"domain_scores_gemma":[0.9996753,0.00001122996,0.00008103144,0.0001655176,0.00001767384,0.0000492358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001974234,0.0003222576,0.2029835,0.00001112431,0.0001484257,0.0000167966,0.0001875056,0.01433389,0.7783189,0.0007705482,0.00002384597,0.002685755],"study_design_scores_gemma":[0.01060234,0.002357036,0.6811337,0.00002921038,0.0002124269,0.0000326315,0.0002535157,0.001262385,0.2871681,0.008906408,0.007059519,0.0009826517],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929119,0.00469263,0.0008558343,0.0002615669,0.0005062484,0.0002348014,0.00009185031,0.00001332047,0.000431809],"genre_scores_gemma":[0.9976111,0.00002691604,0.001024941,0.00006879521,0.0002140885,0.00005128678,0.0007803179,0.00002528,0.0001972841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4911507,"threshold_uncertainty_score":0.6897657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011252157640957,"score_gpt":0.2665426512534259,"score_spread":0.2564301296770163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}