{"id":"W4220795539","doi":"10.3389/fmicb.2022.869164","title":"Virulence of Emerging Arthrotropic Avian Reoviruses Correlates With Their Ability to Activate and Traffic Interferon-γ Producing Cytotoxic CD8+ T Cells Into Gastrocnemius Tendon","year":2022,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Chicken Farmers of Saskatchewan; Ministry of Agriculture - Saskatchewan","keywords":"Cytotoxic T cell; Biology; Virulence; CD8; Pathogenesis; Virology; Immunology; Immune system; Virus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008296808,0.0001943669,0.000102119,0.0001542227,0.00006431409,0.0001919914,0.00007641444,0.0001896472,0.0004405395],"category_scores_gemma":[0.0001218495,0.00009561821,0.0001352035,0.00005919155,0.0001290523,0.0001352163,0.0001224352,0.0002757133,0.0001184586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001391745,"about_ca_system_score_gemma":0.00009713106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006919667,"about_ca_topic_score_gemma":0.001010285,"domain_scores_codex":[0.9999135,0.00001212565,0.000008803639,0.00002256258,0.00001565127,0.0000274156],"domain_scores_gemma":[0.999869,0.00001871777,0.00005184961,0.00001047817,0.00002128953,0.00002860372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007998005,0.00001552251,0.006117719,0.00002006732,0.000004256498,0.00004752419,0.00002566904,0.00005258407,0.9931284,0.00001468803,0.000007060062,0.0004864141],"study_design_scores_gemma":[0.00002097969,0.00217715,0.4665101,0.00002110227,0.00004567298,0.001311049,0.0005022488,0.001860819,0.5266634,0.00008570842,0.0007887261,0.00001310384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999383,0.0001402523,0.0001794888,0.000006145576,0.000001539525,0.000004141193,0.00004137042,0.000003568481,0.0002404413],"genre_scores_gemma":[0.9991364,0.0001193309,0.0002908427,0.00000664548,0.000001527992,0.000005610194,0.0001176837,0.000001786254,0.0003201657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006919667,"threshold_uncertainty_score":0.001473725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009188997123077221,"score_gpt":0.2455628455611161,"score_spread":0.2363738484380389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}