{"id":"W4220814517","doi":"10.1155/2022/7299778","title":"Potential Therapeutic Applications of Plant-Derived Alkaloids against Inflammatory and Neurodegenerative Diseases","year":2022,"lang":"en","type":"review","venue":"Evidence-based Complementary and Alternative Medicine","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Christie (Canada)","funders":"","keywords":"Galantamine; Berberine; Alkaloid; Pharmacology; Drug; Sophora flavescens; Context (archaeology); Harmine; Oxymatrine; Traditional medicine; Medicine; Chemistry; Biology; Disease; Donepezil; Dementia; Stereochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390535,0.0005514717,0.0009020696,0.001927078,0.0002081121,0.0007464589,0.0004475903,0.0006874288,0.003980464],"category_scores_gemma":[0.0004886376,0.0001941593,0.0008409543,0.0009904815,0.0001986238,0.0005923279,0.0003785888,0.000633193,0.0008579408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00026644,"about_ca_system_score_gemma":0.0006846514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006662697,"about_ca_topic_score_gemma":0.001962411,"domain_scores_codex":[0.9998581,0.00003092014,0.00002525454,0.00002897098,0.00004446208,0.0000122589],"domain_scores_gemma":[0.9998386,0.00008555089,0.00003227981,0.00000541193,0.0000292224,0.000008929864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002530104,0.0002233725,0.000774737,0.1068489,0.0006341512,0.0007151449,0.0001633273,0.001298081,0.01647534,0.004374291,0.007395152,0.8608446],"study_design_scores_gemma":[0.0001387418,0.0007585949,0.006771059,0.0216159,0.00192608,0.004717404,0.0002528508,0.0008364719,0.008559613,0.004209674,0.9501426,0.00007117038],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001404266,0.9963503,0.0002775685,0.0001806895,0.00006107474,0.00001428537,0.00008358929,0.00001307851,0.001615176],"genre_scores_gemma":[0.01052568,0.9875737,0.0008089337,0.0001866045,0.00005922924,0.00001668588,0.0001164923,0.00000371362,0.0007088393],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003980464,"threshold_uncertainty_score":0.01331598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1259780775161279,"score_gpt":0.3802271200287267,"score_spread":0.2542490425125988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}