{"id":"W4220828655","doi":"10.2174/1570159x20666220327220929","title":"Naked Mole-Rat Cortex Maintains Reactive Oxygen Species HomeostasisDuring <i>In Vitro</i> Hypoxia or Ischemia and Reperfusion","year":2022,"lang":"en","type":"article","venue":"Current Neuropharmacology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ontario Research Foundation","keywords":"Reactive oxygen species; Oxidative stress; Homeostasis; Hypoxia (environmental); Superoxide; Mitochondrion; Chemistry; Ischemia; Mitochondrial ROS; Cell biology; Biology; Biochemistry; Oxygen; Internal medicine; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001757224,0.0002386378,0.0002621656,0.0001388231,0.0002515948,0.00001452623,0.0002079515,0.00009188803,0.0004846294],"category_scores_gemma":[0.0001047484,0.0002349278,0.00007647178,0.000194118,0.0001289899,0.000006648598,0.0006038346,0.0004876321,0.00000988479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000543857,"about_ca_system_score_gemma":0.000107632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004311333,"about_ca_topic_score_gemma":0.000006250802,"domain_scores_codex":[0.9980007,0.0004377206,0.0003100902,0.0007163733,0.0001381509,0.0003969507],"domain_scores_gemma":[0.9993775,0.00006223677,0.0001361692,0.0002541345,0.0000431445,0.00012675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002892752,0.0001610471,0.000462979,0.00002083995,0.0000170624,0.0001708851,0.00009403002,0.00003804425,0.9873394,0.00003726546,0.00659551,0.002170211],"study_design_scores_gemma":[0.002389593,0.0005974398,0.001684703,0.000003751611,0.00003586318,0.0003368153,0.0001868175,0.0000945647,0.618212,0.00001450489,0.3761495,0.0002943877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940739,0.00111644,0.00005399929,0.0003205055,0.003478925,0.0004092266,0.00008241459,0.00002620855,0.0004383898],"genre_scores_gemma":[0.9950676,0.001269249,0.00007721616,0.001248142,0.0004607061,0.0001573314,0.0002367994,0.00003929082,0.001443654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.369554,"threshold_uncertainty_score":0.9580076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02109983020996527,"score_gpt":0.2757090916970182,"score_spread":0.2546092614870529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}