{"id":"W4220828655","doi":"10.2174/1570159x20666220327220929","title":"Naked Mole-Rat Cortex Maintains Reactive Oxygen Species HomeostasisDuring <i>In Vitro</i> Hypoxia or Ischemia and Reperfusion","year":2022,"lang":"en","type":"article","venue":"Current Neuropharmacology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ontario Research Foundation","keywords":"Reactive oxygen species; Oxidative stress; Homeostasis; Hypoxia (environmental); Superoxide; Mitochondrion; Chemistry; Ischemia; Mitochondrial ROS; Cell biology; Biology; Biochemistry; Oxygen; Internal medicine; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001918882,0.0005108256,0.0003019935,0.0002687735,0.0001718651,0.0003184901,0.0002831622,0.0002643865,0.001505877],"category_scores_gemma":[0.0001417185,0.0001882864,0.0002715199,0.0001317272,0.000317533,0.0003842681,0.0002541365,0.0005264138,0.0004775911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002124887,"about_ca_system_score_gemma":0.0002967363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001650489,"about_ca_topic_score_gemma":0.001979798,"domain_scores_codex":[0.9998521,0.000009458696,0.0000137918,0.00005228859,0.00003105335,0.00004121228],"domain_scores_gemma":[0.9997417,0.00002599817,0.0001074035,0.00003750794,0.0000298443,0.00005755895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001627608,0.00001708233,0.0001596385,0.00003658392,0.000005514299,0.00002961792,0.00002043729,0.0000316941,0.9989904,0.00005316055,0.00002270343,0.0004703846],"study_design_scores_gemma":[0.00001050762,0.0003412929,0.004094603,0.000008324435,0.00002687251,0.0001610962,0.00006011483,0.0004366968,0.9935791,0.00003006795,0.001245087,0.000006059038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947423,0.001015993,0.002440407,0.00007501457,0.00005538844,0.00002127089,0.0006545437,0.0001063183,0.0008887953],"genre_scores_gemma":[0.9904876,0.001077586,0.003721636,0.0000627736,0.0000188303,0.00005531451,0.001118107,0.00004529401,0.003412902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001650489,"threshold_uncertainty_score":0.005037665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02109983020996527,"score_gpt":0.2757090916970182,"score_spread":0.2546092614870529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}