{"id":"W4220831558","doi":"10.3390/cancers14071663","title":"In Silico Bioinformatics Followed by Molecular Validation Using Archival FFPE Tissue Biopsies Identifies a Panel of Transcripts Associated with Severe Asthma and Lung Cancer","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Al Jalila Foundation","keywords":"Lung cancer; Medicine; Cancer; Periostin; Transcriptome; Cancer research; Pathology; Biology; Internal medicine; Gene expression; Extracellular matrix; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364034,0.0007363142,0.0008772179,0.00139157,0.0007490359,0.001126624,0.0004300255,0.0005835549,0.002259424],"category_scores_gemma":[0.001577771,0.0002998058,0.001519377,0.001090085,0.0005185375,0.0002145454,0.0006003735,0.0007553344,0.001475108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004995943,"about_ca_system_score_gemma":0.001025888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002178733,"about_ca_topic_score_gemma":0.004880134,"domain_scores_codex":[0.99906,0.0001489576,0.00006074775,0.000354523,0.0002132399,0.0001626733],"domain_scores_gemma":[0.9992905,0.0004010349,0.00008532373,0.00006330292,0.0001209146,0.00003893083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002531888,0.0004066909,0.1654517,0.00249829,0.0005951572,0.002202858,0.0005628543,0.01660083,0.7474694,0.001024011,0.007580284,0.05307597],"study_design_scores_gemma":[0.0003362135,0.001653897,0.5850143,0.0006215022,0.001485919,0.005668935,0.001573656,0.1296976,0.2168973,0.00482394,0.05209127,0.0001354409],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9072185,0.003976064,0.03588518,0.0007033211,0.0001509723,0.0004050714,0.04677093,0.001422738,0.003467239],"genre_scores_gemma":[0.8325958,0.002115407,0.06591016,0.0009286721,0.00005256241,0.0008528743,0.09467227,0.0002650363,0.002607197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002259424,"threshold_uncertainty_score":0.007558584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555418565233607,"score_gpt":0.3037279770847644,"score_spread":0.2881737914324283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}